[HTML][HTML] Redox metabolism: ROS as specific molecular regulators of cell signaling and function

C Lennicke, HM Cochemé - Molecular Cell, 2021 - cell.com
Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Therapeutic approaches for Duchenne muscular dystrophy

TC Roberts, MJA Wood, KE Davies - Nature Reviews Drug Discovery, 2023 - nature.com
Duchenne muscular dystrophy (DMD) is a monogenic muscle-wasting disorder and a
priority candidate for molecular and cellular therapeutics. Although rare, it is the most …

[HTML][HTML] Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights

SA Mason, AJ Trewin, L Parker, GD Wadley - Redox biology, 2020 - Elsevier
Antioxidant supplements are commonly consumed by endurance athletes to minimize
exercise-induced oxidative stress, with the intention of enhancing recovery and improving …

[HTML][HTML] Duchenne muscular dystrophy: from diagnosis to therapy

MS Falzarano, C Scotton, C Passarelli, A Ferlini - Molecules, 2015 - mdpi.com
Duchenne muscular dystrophy (DMD) is an X-linked inherited neuromuscular disorder due
to mutations in the dystrophin gene. It is characterized by progressive muscle weakness and …

The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system

T Kietzmann, A Petry, A Shvetsova… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are among the leading causes of death worldwide. Reactive
oxygen species (ROS) can act as damaging molecules but also represent central hubs in …

Protein S-nitrosylation in health and disease: a current perspective

MW Foster, DT Hess, JS Stamler - Trends in molecular medicine, 2009 - cell.com
Protein S-nitrosylation constitutes a large part of the ubiquitous influence of nitric oxide on
cellular signal transduction and accumulating evidence indicates important roles for S …

[HTML][HTML] Regulation by S-nitrosylation of protein post-translational modification

DT Hess, JS Stamler - Journal of Biological Chemistry, 2012 - ASBMB
Protein post-translational modification by S-nitrosylation conveys a ubiquitous influence of
nitric oxide on signal transduction in eukaryotic cells. The wide functional purview of S …

Oxidative stress signaling to chromatin in health and disease

S Kreuz, W Fischle - Epigenomics, 2016 - Taylor & Francis
Oxidative stress has a significant impact on the development and progression of common
human pathologies, including cancer, diabetes, hypertension and neurodegenerative …

Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease

G Giuliani, M Rosina, A Reggio - The FEBS journal, 2022 - Wiley Online Library
The characterization of fibro/adipogenic progenitor cells (FAPs) in the skeletal muscle has
contributed to modify the monocentric view of muscle regeneration beyond muscle satellite …

A review of progress in o-aminobenzamide-based HDAC inhibitors with dual targeting capabilities for cancer therapy

WX Zhang, J Huang, XY Tian, YH Liu, MQ Jia… - European journal of …, 2023 - Elsevier
Histone deacetylases, as a new class of anticancer targets, could maintain homeostasis by
catalyzing histone deacetylation and play important roles in regulating the expression of …