Management of Acute and Recurrent Pericarditis: JACC State-of-the-Art Review
JG Chiabrando, A Bonaventura, A Vecchié… - Journal of the American …, 2020 - jacc.org
Pericarditis refers to the inflammation of the pericardial layers, resulting from a variety of
stimuli triggering a stereotyped immune response, and characterized by chest pain …
stimuli triggering a stereotyped immune response, and characterized by chest pain …
Interleukin-1 beta as a target for atherosclerosis therapy: biological basis of CANTOS and beyond
P Libby - Journal of the American College of Cardiology, 2017 - jacc.org
Inflammatory pathways drive atherogenesis and link conventional risk factors to
atherosclerosis and its complications. One inflammatory mediator has come to the fore as a …
atherosclerosis and its complications. One inflammatory mediator has come to the fore as a …
The NLRP3 inflammasome in acute myocardial infarction
The heart is extremely sensitive to ischaemic injury. During an acute myocardial infarction
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases
An intense, stereotyped inflammatory response occurs in response to ischaemic and non-
ischaemic injury to the myocardium. The NACHT, LRR and PYD domains-containing protein …
ischaemic injury to the myocardium. The NACHT, LRR and PYD domains-containing protein …
Post-Stroke Cardiovascular Complications and Neurogenic Cardiac Injury: JACC State-of-the-Art Review
Over 1.5 million deaths worldwide are caused by neurocardiogenic syndromes.
Furthermore, the consequences of deleterious brain-heart interactions are not limited to fatal …
Furthermore, the consequences of deleterious brain-heart interactions are not limited to fatal …
From C-reactive protein to interleukin-6 to interleukin-1: moving upstream to identify novel targets for atheroprotection
PM Ridker - Circulation research, 2016 - Am Heart Assoc
Plasma levels of the inflammatory biomarker high-sensitivity C-reactive protein (hsCRP)
predict vascular risk with an effect estimate as large as that of total or high-density …
predict vascular risk with an effect estimate as large as that of total or high-density …
The inflammatory response in myocardial injury, repair, and remodelling
NG Frangogiannis - Nature Reviews Cardiology, 2014 - nature.com
Myocardial infarction triggers an intense inflammatory response that is essential for cardiac
repair, but which is also implicated in the pathogenesis of postinfarction remodelling and …
repair, but which is also implicated in the pathogenesis of postinfarction remodelling and …
Inflammation as a driver of adverse left ventricular remodeling after acute myocardial infarction
PC Westman, MJ Lipinski, D Luger, R Waksman… - Journal of the American …, 2016 - jacc.org
Abstract Treatment of acute myocardial infarction (AMI) has improved significantly in recent
years, but many patients have adverse left ventricular (LV) remodeling, a maladaptive …
years, but many patients have adverse left ventricular (LV) remodeling, a maladaptive …
Anticytokine agents: targeting interleukin signaling pathways for the treatment of atherothrombosis
PM Ridker - Circulation research, 2019 - Am Heart Assoc
The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated
through both adaptive and innate immunity has led to the hypothesis that anticytokine …
through both adaptive and innate immunity has led to the hypothesis that anticytokine …
Role of NLRP3 inflammasome in the pathogenesis of cardiovascular diseases
D Liu, X Zeng, X Li, JL Mehta, X Wang - Basic research in cardiology, 2018 - Springer
NLRP3 inflammasome is a key multiprotein signaling platform that tightly controls
inflammatory responses and coordinates antimicrobial host defenses by activating caspase …
inflammatory responses and coordinates antimicrobial host defenses by activating caspase …