CTRP3 protected against doxorubicin-induced cardiac dysfunction, inflammation and cell death via activation of Sirt1

YP Yuan, ZG Ma, X Zhang, SC Xu, XF Zeng… - Journal of molecular and …, 2018 - Elsevier
Background Inflammation and myocytes apoptosis play critical roles in the development of
doxorubicin (DOX)-induced cardiotoxicity. Our previous study found that C1q/tumour …

[HTML][HTML] Acute and post-acute COVID-19 cardiovascular complications: a comprehensive review

C Kole, Ε Stefanou, N Karvelas, D Schizas… - … drugs and therapy, 2023 - Springer
Abstract Purpose of Review The risk of cardiovascular complications due to SARS-CoV-2
are significantly increased within the first 6 months of the infection. Patients with COVID-19 …

Effects of curcumin nanoparticles in isoproterenol‐induced myocardial infarction

PM Boarescu, I Chirilă, AE Bulboacă… - Oxidative medicine …, 2019 - Wiley Online Library
Curcumin has anti‐inflammatory, antioxidative, anticarcinogenic, and cardiovascular
protective effects. Our study is aimed at evaluating the effects of pretreatment with curcumin …

Effects of Interleukin 17 on the cardiovascular system

M Robert, P Miossec - Autoimmunity reviews, 2017 - Elsevier
Cardiovascular diseases remain the leading cause of death worldwide and account for most
of the premature mortality observed in chronic inflammatory diseases. Common …

Redox regulation of cardiovascular inflammation–Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species

P Wenzel, S Kossmann, T Münzel, A Daiber - Free Radical Biology and …, 2017 - Elsevier
Oxidative stress is a major hallmark of cardiovascular diseases although a causal link was
so far not proven by large clinical trials. However, there is a close association between …

Pharmacologic inhibition of the NLRP3 inflammasome preserves cardiac function after ischemic and nonischemic injury in the mouse

C Marchetti, S Toldo, J Chojnacki… - Journal of …, 2015 - journals.lww.com
Background: Sterile inflammation resulting from myocardial injury activates the NLRP3
inflammasome and amplifies the inflammatory response mediating further damage …

Effects of colchicine on risk of cardiovascular events and mortality among patients with gout: a cohort study using electronic medical records linked with Medicare …

DH Solomon, CC Liu, IH Kuo, A Zak… - Annals of the rheumatic …, 2016 - ard.bmj.com
Background Colchicine may have beneficial effects on cardiovascular (CV) disease, but
there are sparse data on its CV effect among patients with gout. We examined the potential …

Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot …

A Abbate, MC Kontos, NA Abouzaki… - The American journal of …, 2015 - Elsevier
Two pilot studies of interleukin-1 (IL-1) blockade in ST-segment elevation myocardial
infarction (STEMI) showed blunted acute inflammatory response and overall favorable …

[HTML][HTML] Inflammation and oxidative stress in salt sensitive hypertension; The role of the NLRP3 inflammasome

LA Ertuglu, AP Mutchler, J Yu, A Kirabo - Frontiers in Physiology, 2022 - frontiersin.org
Salt-sensitivity of blood pressure is an independent risk factor for cardiovascular disease
and affects approximately half of the hypertensive population. While the precise …

Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets

JWE Moss, DP Ramji - Future medicinal chemistry, 2016 - Taylor & Francis
Atherosclerosis, the primary cause of cardiovascular disease (CVD), is a chronic
inflammatory disorder in the walls of medium and large arteries. CVD is currently …