With the rapid development of artificial intelligence (AI) technologies, and the large amount
of pharmacovigilance-related data stored in an electronic manner, data-driven automatic …

Diabetes poses a significant global health challenge, necessitating innovative therapeutic
strategies. Natural products and their derivatives have emerged as promising candidates for …

Much has been written and said about the promise and excitement of microphysiological
systems, miniature devices that aim to recreate aspects of human physiology on a chip. The …

Abstract In 2013, the Global Coalition for Regulatory Science Research (GCRSR) was
established with members from over ten countries (www. gcrsr. net). One of the main …

In an increasingly interconnected world, ensuring the safety of the global food supply has
emerged as a paramount concern. With foodborne illnesses affecting millions annually and …

Identifying patient cohorts meeting the criteria of specific phenotypes is essential in
biomedicine and particularly timely in precision medicine. Many research groups deliver …

In 2012, 20 key questions related to hazard and exposure assessment and environmental
and health risks of pharmaceuticals and personal care products in the natural environment …

Animals and animal models have been invaluable for our current understanding of human
and animal biology, including physiology, pharmacology, biochemistry, and disease …

Systematic review and evaluation of mechanistic evidence using the Key Characteristics
approach was proposed by the International Agency for Research on Cancer (IARC) in 2012 …

Human cell-based test methods can be used to evaluate potential hazards of mixtures and
products of petroleum refining (“unknown or variable composition, complex reaction …