Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma

S Tan, J Zhao, Z Sun, S Cao, K Niu… - Proceedings of the …, 2020 - National Acad Sciences
Transforming growth factor β-activated kinase1 (TAK1) encoded by the gene MAP3K7
regulates multiple important downstream effectors involved in immune response, cell death …

Alpha‐fetoprotein production by hepatocellular carcinoma is prognostic of poor patients survival

R Izumi, K Shimizu, M Kiriyama… - Journal of surgical …, 1992 - Wiley Online Library
Immunohistochemistry using the avidinbiotinperoxidase complex method was performed to
study the production of alphafetoprotein (AFP) in hepatocellular carcinoma (HCC) tissue …

Monitoring of lectin-reactive α-fetoproteins in patients with hepatocellular carcinoma treated using transcatheter arterial embolization

F Yamashita, M Tanaka, S Satomura… - European journal of …, 1995 - journals.lww.com
Objective: To evaluate the value of lectin-reactive α-fetoprotein (LR-AFP) levels for
assessing therapeutic effects and for predicting prognosis in patients with hepatocellular …

Chemiluminescent enzyme immunoassay of alpha-fetoprotein based on an adamantyl dioxetane phenyl phosphate substrate.

GH Thorpe, I Bronstein, LJ Kricka, B Edwards… - Clinical …, 1989 - academic.oup.com
We have evaluated a new chemiluminescent substrate for the alkaline phosphatase (EC 3.1.
3.1) label used in a Hybritech Tandem-E immunoassay of alpha-fetoprotein (AFP). The new …

[PDF][PDF] Función del sistema inmune en la defensa contra tumores malignos

A Duharte - Medisan, 2003 - academia.edu
La inmunoterapia se perfila como el cuarto pilar en el tratamiento de las neoplasias
malignas, luego de las formas ya establecidas: cirugía, radioterapia y quimioterapia; sin …

Markers for hepatocellular carcinoma

AHB Wu, SS Sell - Immunodiagnosis of cancer, 2017 - api.taylorfrancis.com
As with all neoplastic processes, causative factors in human hepatocellular carcinoma are
complex and involve a mix of genetic and environmental factors. Cancers that originate from …

Evaluation of epidermal growth factor receptor, carcinoembryonic antigen and Lewis carbohydrate antigens in human colorectal and liver neoplasias

A Di Carlo, A Mariano, V D'Alessandro… - Oncology …, 2001 - spandidos-publications.com
The expression of LewisY related carbohydrate antigens and the content of epidermal
growth factor receptor (EGF-R), the carcinoembryonic antigen (CEA) and the α-fetoprotein …

Serum α-fetoprotein levels and microheterogeneity in patients with different liver diseases

JA Nikolić, M Stajić, M Čuperlović, L Hajduković… - Journal of …, 1990 - Elsevier
Serum α-fetoprotein levels were determined in patients (268) with liver disease. Markedly
elevated concentrations (> 100 μg/l) were found in twelve patients with malignant tumours …

[PDF][PDF] Markedly increased alpha-fetoprotein concentration in serum in alcoholic liver disease: malignant tumor or nonneoplastic changes?

J Kaczynski, R Jagenburg, G Lindstedt, S Wallerstedt - Clinical chemistry, 1992 - Citeseer
DIscussion Several diagnostic alternatives may be considered for our patient. One is that he
initially did have a hepato-cellular(or other) carcinoma, which regressed spontaneously and …

[PDF][PDF] Radioimmunoassayists must embrace new technology

LR Witherspoon - Journal of Nuclear Medicine, 1989 - Soc Nuclear Med
(28). They also provide a means to protect the nation's blood supply from contamination with
hepatitis and human immunodeficiency viruses. Today, immunoassays provide impor tant …