T-cells are crucial in maintanence of intestinal homeostasis, however, it is still unclear how
microbiota metabolites regulate T-effector cells. Here we show gut microbiota-derived short …

The gut microbiota has an important role in the gut barrier, inflammation and metabolic
functions. Studies have identified a close association between the intestinal barrier and …

The gastrointestinal tract harbors most of the microbiota associated with humans. In recent
years, there has been a surge of interest in assessing the relationships between the gut …

Inflammatory bowel diseases (IBD) can be broadly divided into Crohn's disease (CD) and
ulcerative colitis (UC) from their clinical phenotypes. Over 150 host susceptibility genes have …

Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), are complex chronic inflammatory conditions of the gastrointestinal tract that are driven …

Research over the last 7 years has led to the formal identification of innate lymphoid cells
(ILCs), increased the understanding of their tissue distribution and has established essential …

Ferroptosis has recently emerged as an iron-dependent form of nonapoptotic cell death,
which is also a regulated necrosis process and a response to tumor suppression. However …

A trace element, known as a minor element, is a chemical element whose concentration is
very low. They are divided into essential and non-essential classes. Numerous physiological …

Akkermansia muciniphila is potential probiotic in that its type strain ATCC BAA-835 has
beneficial effects upon obesity and diabetes. However, whether A. muciniphila can improve …

There is a clinical need for new, more effective treatments for chronic and debilitating
inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. In this …