Enteroendocrine cells and gut hormones as potential targets in the crossroad of the gut-kidney axis communication

JAO Nery Neto, VY Yariwake, NOS Câmara… - Frontiers in …, 2023 - frontiersin.org
Recent studies suggest that disruptions in intestinal homeostasis, such as changes in gut
microbiota composition, infection, and inflammatory-related gut diseases, can be associated …

Responsiveness of afferent renal nerve units in renovascular hypertension in rats

K Rodionova, KF Hilgers, S Rafii-Tabrizi… - … -European Journal of …, 2021 - Springer
Previous data suggest that renal afferent nerve activity is increased in hypertension exerting
sympathoexcitatory effects. Hence, we wanted to test the hypothesis that in renovascular …

Neurogenic substance P—influences on action potential production in afferent neurons of the kidney?

K Rodionova, KF Hilgers, P Linz, J Schätzl… - … -European Journal of …, 2021 - Springer
We recently showed that a substance P (SP)–dependent sympatho-inhibitory mechanism
via afferent renal nerves is impaired in mesangioproliferative nephritis. Therefore, we tested …

Involvement of NOX-4/JAK/STAT pathway in the protective effect of aprepitant against diclofenac-induced renal toxicity

HM Hafez, S Waz, RA Rifaai, MZ Mohamed - Life Sciences, 2022 - Elsevier
Abstract Aims Aprepitant, a neurokinin-1 (NK1) receptor antagonist, is a clinically approved
anti-emetic drug. Recently, inhibition of the NK1 receptor has been reported as a potential …

Myocardial infarction with a preserved ejection fraction—the impaired function of the cardio-renal baroreflex

L Pickny, M Hindermann, T Ditting, KF Hilgers… - Frontiers in …, 2023 - frontiersin.org
Introduction: In experimental myocardial infarction with reduced ejection fraction causing
overt congestive heart failure, the control of renal sympathetic nerve activity (RSNA) by the …

Renal nerve ablation in nephritis and beyond

K Rodionova, T Ditting, R Veelken - Journal of the American …, 2021 - journals.lww.com
Sympathetic nerves innervate the kidney and help regulate glomerular perfusion and
filtration, and after renal denervation, altered regulation may affect the course of kidney …

[HTML][HTML] Cardioprotective action of aprepitant in a rat model of ischemia-reperfusioninduced myocardial injury: role of PI3K-AkT-GSK-3β-HIF-1α signaling pathway

M Qian, Y Liu - Acta Cirúrgica Brasileira, 2022 - SciELO Brasil
Purpose: The present study explored the role and mechanism involved in aprepitant-
induced cardioprotective effects in rat model of ischemia-reperfusion injury. Methods: The …

[PDF][PDF] Die verminderte Erregbarkeit renaler Afferenzen nach Chemokinexposition

N Lale - 2023 - opus4.kobv.de
Zusammenfassung Hintergrund und Ziele Die autonome Innervation der Niere steht im
Zusammenhang mit der Entstehung von arterieller Hypertonie aber auch mit entzündlichen …