The present study analyzed the concentration of renin-like activity and angiotensinogen
concentration (AoC) in different brain areas related to cardiovascular control in SHR and …

The present experiments were designed to document changes in the regional distribution of
angiotensinogen in the rat brain with the development of hypertension in spontaneously …

The converting enzyme inhibitors (CEI) SA446 and Captopril (CAP) were given orally at a
dose 50 mg/kg per day to adult stroke-prone spontaneously hypertensive rats (SHRSP) over …

Brain renin-angiotensin system plays an important role in blood pressure regulation and is
suggested to play a role in the development and maintenance of hypertension. To test the …

The central nervous and systemic kinetics of ramipril, an angiotensin-converting enzyme
inhibitor prodrug, and its active metabolite ramiprilat were studied in conscious beagle dogs …

The role of the brain kallikrein-kinin system in the regulation of arterial blood pressure of
normotensive and spontaneously hypertensive rats was evaluated. Intracerebroventricular …

We describe a quantitative autoradiographic technique which allows measurement of
angiotensin-I-converting enzyme [ACE](kininase II, peptidyldipeptide hydrolase, EC 3.4 …

The brain renin-angiotensin system (RAS) has been suggested as contributing to the
pathogenesis of spontaneous hypertension in rats. Brain angiotensinogen-and angiotensin …

Primary cultures from fetal rat brain contain angiotensin II immunoreactivity in neurons. To
study the origin of this immunoreactivity, primary cultures were incubated with [3H]-valine or …

The previous volume on Antihypertensive Agents in the Handbook of Experi mental
Pharmacology, published in 1977, was edited by the late Franz Gross from the Department …