Targeting cancer-promoting inflammation—have anti-inflammatory therapies come of age?
The immune system has crucial roles in cancer development and treatment. Whereas
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …
Prostaglandin E2 and cancer: insight into tumor progression and immunity
F Finetti, C Travelli, J Ercoli, G Colombo, E Buoso… - Biology, 2020 - mdpi.com
Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …
recognized that there exists a direct causal link between inflammation and tumors. Among …
Cardiovascular effects and safety of (non-aspirin) NSAIDs
AM Schjerning, P McGettigan, G Gislason - Nature Reviews Cardiology, 2020 - nature.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective, widely used analgesics. For
the past 2 decades, considerable attention has been focused on their cardiovascular safety …
the past 2 decades, considerable attention has been focused on their cardiovascular safety …
[HTML][HTML] Therapeutic potential of targeting the Wnt/β-catenin signaling pathway in colorectal cancer
X Cheng, X Xu, D Chen, F Zhao, W Wang - Biomedicine & …, 2019 - Elsevier
Aberrant Wnt/β-catenin signaling has often been reported in different cancers, particularly
colorectal cancer (CRC), and this signaling cascade is central to carcinogenesis …
colorectal cancer (CRC), and this signaling cascade is central to carcinogenesis …
Cardiovascular safety of celecoxib, naproxen, or ibuprofen for arthritis
Background The cardiovascular safety of celecoxib, as compared with nonselective
nonsteroidal antiinflammatory drugs (NSAIDs), remains uncertain. Methods Patients who …
nonsteroidal antiinflammatory drugs (NSAIDs), remains uncertain. Methods Patients who …
Bodywide ecological interventions on cancer
Historically, cancer research and therapy have focused on malignant cells and their tumor
microenvironment. However, the vascular, lymphatic and nervous systems establish long …
microenvironment. However, the vascular, lymphatic and nervous systems establish long …
Guidelines for colonoscopy surveillance after screening and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer
DA Lieberman, DK Rex, SJ Winawer… - …, 2012 - gastrojournal.org
Screening for colorectal cancer (CRC) in asymptomatic patients can reduce the incidence
and mortality of CRC. In the United States, colonoscopy has become the most commonly …
and mortality of CRC. In the United States, colonoscopy has become the most commonly …
Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening
E Quintero, A Castells, L Bujanda… - … England Journal of …, 2012 - Mass Medical Soc
Background Colonoscopy and fecal immunochemical testing (FIT) are accepted strategies
for colorectal-cancer screening in the average-risk population. Methods In this randomized …
for colorectal-cancer screening in the average-risk population. Methods In this randomized …
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
Colorectal cancer chemotherapy: the evolution of treatment and new approaches
RM McQuade, V Stojanovska… - Current medicinal …, 2017 - ingentaconnect.com
Colorectal cancer (CRC) is one the greatest contributors to cancer related mortality.
Although 5 year survival rate for patients at the early stage of CRC (stages I and II) is above …
Although 5 year survival rate for patients at the early stage of CRC (stages I and II) is above …