The human microbiome orchestrates a variety of metabolic, immunological and regulatory
functions in health and disease. However, experimentally dissecting host–microbiome …

Despite the highly infectious nature of the SARS-CoV-2 virus, it is clear that some individuals
with potential exposure, or even experimental challenge with the virus, resist developing a …

Due to the paucity of longitudinal molecular studies of COVID-19, particularly those covering
the early stages of infection (Days 1-8 symptom onset), our understanding of host response …

Introduction The spectrum of SARS-CoV-2 mutations have increased over time, resulting in
the emergence of several variants of concern. Persistent infection is assumed to be involved …

Ribosomal frameshifting (RFS) at the slippery site of SARS-CoV-2 RNA is essential for the
biosynthesis of the viral replication machinery. It requires the formation of a pseudoknot (PK) …

The emergence of novel betacoronaviruses has posed significant financial and human
health burdens, necessitating the development of appropriate tools to combat future …

Outbreaks of emerging infectious diseases pose a serious threat to public health security,
human health and economic development. After an outbreak, an animal model for an …

COVID-19, along with most respiratory diseases in the medical field, demonstrates
significant ability to take its toll on global population. There is a particular difficulty in …

Epidemiological evidence emphasizes that excess fat mass is associated with an increased
risk of severe COVID-19 disease. Nevertheless, the intricate interplay between SARS-CoV-2 …

Here, we propose the molecular hybridization of dihydroartemisinin (DHA) and
ursodeoxycholic bile acid (UDCA), approved drugs, for the preparation of antiviral agents …