Molecular pathways of rosmarinic acid anticancer activity in triple-negative breast cancer cells: a literature review

EK Konstantinou, AA Panagiotopoulos, K Argyri… - Nutrients, 2023 - mdpi.com
Breast cancer is the most frequent type of cancer in women. Oncogenic transcription factors
promote the overproduction of cellular adhesion molecules and inflammatory cytokines …

Omission of radiotherapy after breast-conserving surgery for women with breast cancer with low clinical and genomic risk: 5-year outcomes of IDEA

R Jagsi, KA Griffith, EE Harris, JL Wright… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Multiple studies have shown a low risk of ipsilateral breast events (IBEs) or other
recurrences for selected patients age 65-70 years or older with stage I breast cancers …

Molecular Pathways of Genistein Activity in Breast Cancer Cells

EK Konstantinou, A Gioxari, M Dimitriou… - International Journal of …, 2024 - mdpi.com
The most common malignancy in women is breast cancer. During the development of
cancer, oncogenic transcription factors facilitate the overproduction of inflammatory …

Postoperative radiotherapy omission in selected patients with early breast cancer following preoperative breast MRI (PROSPECT): primary results of a prospective two …

GB Mann, AR Skandarajah, N Zdenkowski, J Hughes… - The Lancet, 2024 - thelancet.com
Background Adjuvant breast radiotherapy as a standard component of breast-conserving
treatment for early cancer can overtreat many women. Breast MRI is the most sensitive …

AI improves accuracy, agreement and efficiency of pathologists for Ki67 assessments in breast cancer

A Dy, NNJ Nguyen, J Meyer, M Dawe, W Shi… - Scientific Reports, 2024 - nature.com
The Ki-67 proliferation index (PI) guides treatment decisions in breast cancer but suffers
from poor inter-rater reproducibility. Although AI tools have been designed for Ki-67 …

Integrative radiomics clustering analysis to decipher breast cancer heterogeneity and prognostic indicators through multiparametric MRI

Y He, S Duan, W Wang, H Yang, S Pan, W Cheng… - NPJ Breast …, 2024 - nature.com
Breast cancer diagnosis and treatment have been revolutionized by multiparametric
Magnetic Resonance Imaging (mpMRI), encompassing T2-weighted imaging (T2WI) …

Ki67 assessment protocol as an integral biomarker for avoiding radiotherapy in the LUMINA breast cancer trial

TO Nielsen, SCY Leung, N Riaz, AM Mulligan… - …, 2023 - Wiley Online Library
Aims The LUMINA trial demonstrated a very low local recurrence rate in women≥ 55 years
with low‐risk luminal A breast cancer (defined as grade I‐II, T1N0, hormone receptor …

[HTML][HTML] Quality of Life Outcomes Associated With Optimization of Treatment by Omitting Radiotherapy in Early Breast Cancer

L Stafford, M Sinclair, P Butow, J Hughes, A Park… - Clinical Breast …, 2024 - Elsevier
Purpose Improved prognosis of early breast cancer (EBC) has created opportunities for
treatment optimization but reducing morbidity should not inadvertently compromise quality of …

[PDF][PDF] 腔镜与开放保乳手术治疗早期乳腺癌的近期疗效比较

万安弟, 周于钦, 张聪, 姜军, 张毅, 齐晓伟 - 中国普通外科杂志, 2023 - zpwz.net
摘要背景与目的: 乳腺癌发病率高, 目前以手术治疗为主, 保乳手术(BCS) 是早期乳腺癌常用的
手术方式, 但我国保乳率低, 传统开放保乳术后切口疤痕仍明显. 目前, 具有术后美容效果好 …

Preparation of Porphyrin-Based Unimolecular Micelles for Synergistic Photodynamic Therapy and Radiotherapy

J Song, S Ren, X Xu, S Zhang, W He… - ACS Applied Polymer …, 2024 - ACS Publications
Polymeric carriers have been widely used in biomedical fields because of their strong
structural tunability and biocompatibility, which often proximately determine the in vivo …