Muscle's structural composition is an important factor underlying muscle strength and
physical function in older adults. There is an increasing amount of research to support the …

Muscular dystrophies are a heterogeneous group of inherited disorders that share similar
clinical features and dystrophic changes on muscle biopsy. An improved understanding of …

Background Mutations that disrupt the open reading frame and prevent full translation of
DMD, the gene that encodes dystrophin, underlie the fatal X-linked disease Duchenne …

Driven by increasing numbers of newly identified genetic defects and new insights into the
field of inherited muscle diseases, neuromuscular imaging in general and magnetic …

Muscular weakness developing from critical illness neuropathy, myopathy and muscle
atrophy has been characterized as intensive care unit-acquired weakness (ICUAW). This …

Greenfield's Neuropathology, the world's leading neuropathology reference, provides a
comprehensive account of the pathological findings in neurological disease, their biological …

Purpose The purpose of this study was to assess relationships between intramuscular
adipose tissue (IntraMAT) content determined by MRI and intramyocellular lipids (IMCL) and …

Background Outcome measures for clinical trials in neuromuscular diseases are typically
based on physical assessments which are dependent on patient effort, combine the effort of …

Purpose To analyze T2 maps of pelvic and thigh muscles in Duchenne muscular dystrophy
(DMD), to identify the most severely affected muscle, and to correlate the T2 of muscle with …

This article reviews the indications for a muscle biopsy, and then gives a step-by-step
description of the processes of muscle selection through to interpreting the biopsy report …