Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems
DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …
administration which is associated with greater patient medication adherence. One major …
Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
Recent advances in oral and transdermal protein delivery systems
Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …
Insulin-loaded liposomes packaged in alginate hydrogels promote the oral bioavailability of insulin
H Wu, J Nan, L Yang, HJ Park, J Li - Journal of Controlled Release, 2023 - Elsevier
Compared to subcutaneous injections, oral administration of insulin would be a preferred
route of drug administration for diabetic patients. For oral delivery, both liposomes and …
route of drug administration for diabetic patients. For oral delivery, both liposomes and …
[HTML][HTML] pH-sensitive O-carboxymethyl chitosan/sodium alginate nanohydrogel for enhanced oral delivery of insulin
H Zhang, Z Gu, W Li, L Guo, L Wang, L Guo… - International Journal of …, 2022 - Elsevier
Oral drug delivery is considered the most preferred mode of treatment because of its high
patient compliance and minimal invasiveness. However, the oral delivery of protein drug has …
patient compliance and minimal invasiveness. However, the oral delivery of protein drug has …
Progress and prospects of polysaccharide-based nanocarriers for oral delivery of proteins/peptides
H Yuan, C Guo, L Liu, L Zhao, Y Zhang, T Yin… - Carbohydrate …, 2023 - Elsevier
The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …
Cracking the intestinal lymphatic system window utilizing oral delivery vehicles for precise therapy
YB Miao, T Xu, Y Gong, A Chen, L Zou, T Jiang… - Journal of …, 2023 - Springer
Oral administration is preferred over other drug delivery methods due to its safety, high
patient compliance, ease of ingestion without discomfort, and tolerance of a wide range of …
patient compliance, ease of ingestion without discomfort, and tolerance of a wide range of …
Self-assembled chitosan-insulin oral nanoparticles—A critical perspective review
Chitosan is an abundant natural cationic polysaccharide with excellent biodegradability,
bioadhesion, and biocompatibility. Chitosan is extensively researched for various particulate …
bioadhesion, and biocompatibility. Chitosan is extensively researched for various particulate …
Advances in buccal and oral delivery of insulin
Diabetes mellitus is a metabolic endocrine disease characterized by chronic hyperglycemia
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …
Oral nanomedicine biointeractions in the gastrointestinal tract in health and disease
Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …
compliance of the patient. Oral nanomedicines have been developed to overcome the …