[HTML][HTML] AI-enabled organoids: construction, analysis, and application

L Bai, Y Wu, G Li, W Zhang, H Zhang, J Su - Bioactive Materials, 2024 - Elsevier
Organoids, miniature and simplified in vitro model systems that mimic the structure and
function of organs, have attracted considerable interest due to their promising applications in …

[HTML][HTML] Antitumor applications of photothermal agents and photothermal synergistic therapies

C Li, Y Cheng, D Li, Q An, W Zhang, Y Zhang… - International Journal of …, 2022 - mdpi.com
As a new tumor treatment strategy, photothermal therapy (PTT) has the advantages of
accuracy, ease of administration, a high efficiency and low side effects. Photothermal …

[HTML][HTML] Challenges and prospects of patient-derived xenografts for cancer research

J Jin, K Yoshimura, M Sewastjanow-Silva, S Song… - Cancers, 2023 - mdpi.com
Simple Summary The patient-derived xenograft (PDX) model is the in vivo standard for
cancer research as a preclinical platform. Besides its merits, we describe the general …

Cancer‐associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications

KY Wong, AHK Cheung, B Chen… - … journal of cancer, 2022 - Wiley Online Library
Lung cancer is the common and leading cause of cancer death worldwide. The tumor
microenvironment has been recognized to be instrumental in tumorigenesis. To have a deep …

Patient‐derived cancer organoids for drug screening: basic technology and clinical application

X Ren, W Chen, Q Yang, X Li… - … of Gastroenterology and …, 2022 - Wiley Online Library
Cancer organoids, a three‐dimensional (3D) culture system of cancer cells derived from
tumor tissues, recapitulate physiological structure of the parental tumor. Different tumor …

[HTML][HTML] The application of patient-derived organoid in the research of lung cancer

Y Li, X Gao, C Ni, B Zhao, X Cheng - Cellular Oncology, 2023 - Springer
Lung cancer is the most common cancer and the leading cause of cancer-related death
worldwide. However, mechanisms of its progression remained unclear and new treatments …

3D bioprinted liver tissue and disease models: Current advances and future perspectives

L Sun, Y Wang, S Zhang, H Yang, Y Mao - Biomaterials Advances, 2023 - Elsevier
Abstract Three-dimensional (3D) bioprinting is a promising technology for fabricating
complex tissue constructs with biomimetic biological functions and stable mechanical …

Studying oral tissue via real-time high-resolution terahertz spectroscopic imaging

S Yang, L Ding, S Wang, C Du, L Feng, H Qiu… - Physical Review …, 2023 - APS
Terahertz (THz) waves are extremely sensitive to water content and biological composition
(proteins, genes, and metabolites), which are the key regulator of cancer development …

Prediction of Clinical Precision Chemotherapy by Patient‐Derived 3D Bioprinting Models of Colorectal Cancer and Its Liver Metastases

H Sun, L Sun, X Ke, L Liu, C Li, B Jin, P Wang… - Advanced …, 2024 - Wiley Online Library
Methods accurately predicting the responses of colorectal cancer (CRC) and colorectal
cancer liver metastasis (CRLM) to personalized chemotherapy remain limited due to tumor …

Engineered 3D ex vivo models to recapitulate the complex stromal and immune interactions within the tumor microenvironment

K Ravi, TJM Manoharan, KC Wang, B Pockaj… - Biomaterials, 2023 - Elsevier
Cancer thrives in a complex environment where interactions between cellular and acellular
components, surrounding the tumor, play a crucial role in disease development and …