Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents

A Najmi, SA Javed, M Al Bratty, HA Alhazmi - Molecules, 2022 - mdpi.com
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …

Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019

DJ Newman, GM Cragg - Journal of natural products, 2020 - ACS Publications
This review is an updated and expanded version of the five prior reviews that were
published in this journal in 1997, 2003, 2007, 2012, and 2016. For all approved therapeutic …

COVID-19: A promising cure for the global panic

B Vellingiri, K Jayaramayya, M Iyer… - Science of the total …, 2020 - Elsevier
The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the
causative agent of a potentially fatal disease that is of great global public health concern …

Green Synthesis and Characterization of ZnO Nanoparticles Using Pelargonium odoratissimum (L.) Aqueous Leaf Extract and Their Antioxidant, Antibacterial and …

AS Abdelbaky, TA Abd El-Mageed, AO Babalghith… - Antioxidants, 2022 - mdpi.com
Nanoparticles (NPs) exhibit distinct features compared to traditional physico-chemical
synthesis and they have many applications in a wide range of fields of life sciences such as …

Natural products: A lead for drug discovery and development

B Chopra, AK Dhingra - Phytotherapy Research, 2021 - Wiley Online Library
Natural products are used since ancient times in folklore for the treatment of various
ailments. Plant‐derived products have been recognized for many years as a source of …

Phenols in pharmaceuticals: analysis of a recurring motif

KA Scott, PB Cox, JT Njardarson - Journal of Medicinal Chemistry, 2022 - ACS Publications
Phenols and phenolic ethers are significant scaffolds recurring both in nature and among
approved small-molecule pharmaceuticals. This compendium presents the first …

The role of natural products in modern drug discovery.

JB Calixto - Anais da Academia Brasileira de Ciências, 2019 - SciELO Brasil
The global medicine market is about 1.1 trillion US dollars. About 35 percent of medicines
have originated from natural products. Brazil presents the largest biodiversity in the world …

Natural products as sources of new drugs from 1981 to 2014

DJ Newman, GM Cragg - Journal of natural products, 2016 - ACS Publications
This contribution is a completely updated and expanded version of the four prior analogous
reviews that were published in this journal in 1997, 2003, 2007, and 2012. In the case of all …

A status review on the medicinal properties of essential oils

JS Raut, SM Karuppayil - Industrial crops and products, 2014 - Elsevier
Essential oils (EOs) are complex mixtures of low molecular weight compounds extracted
from plants by steam distillation and various solvents. Terpenoids and phenylpropanoids are …

Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …