Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Polymeric nanoparticle-based nanovaccines for cancer immunotherapy

Y Zhang, J Chen, L Shi, F Ma - Materials Horizons, 2023 - pubs.rsc.org
Therapeutic cancer vaccines, which are designed to amplify tumor-specific T cell responses,
have been envisioned as one of the most powerful tools for effective cancer immunotherapy …

Ferroptosis and Necroptosis Produced Autologous Tumor Cell Lysates Co-Delivering with Combined Immnoadjuvants as Personalized In Situ Nanovaccines for …

W Shi, W Feng, S Li, Y Cui, S Liu, H Jiang, Y Liu… - ACS …, 2023 - ACS Publications
Nanovaccine-based immunotherapy has been considered as a major pillar to stimulate the
host immune system to recognize and eradicate tumor cells as well as establish a long-term …

Recent advances and clinical potential of near infrared photothermal conversion materials for photothermal hepatocellular carcinoma therapy

RL Ge, PN Yan, Y Liu, ZS Li… - Advanced Functional …, 2023 - Wiley Online Library
Growing concern about photothermal tumor therapy (PTT) as a promising alternative to
conventional liver cancer treatment, which is a treatment strategy that utilizes near‐infrared …

Nanomaterials-based tumor microenvironment modulation for magnifying sonodynamic therapy

L Song, L Lu, Y Pu, H Yin, K Zhang - Accounts of Materials …, 2022 - ACS Publications
Conspectus Sonodynamic therapy (SDT) is a noninvasive and more preferable therapeutic
modality than photodynamic therapy (PDT) due to deeper tissue penetration, which utilizes …

A Fluorinated Supramolecular Self‐Assembled Peptide as Nanovaccine Adjuvant for Enhanced Cancer Vaccine Therapy

S Jia, S Ji, J Zhao, Y Lv, J Wang, D Sun… - Small …, 2023 - Wiley Online Library
Adjuvants play an important role in enhancing vaccine‐induced immune protection.
Adequate cellular uptake, robust lysosomal escape, and subsequent antigen cross …

Aluminium nanoparticles as efficient adjuvants compared to their microparticle counterparts: current progress and perspectives

A Nazarizadeh, AH Staudacher, NL Wittwer… - International Journal of …, 2022 - mdpi.com
Aluminium (Al) compounds are used as adjuvants in human and veterinary prophylactic
vaccines due to their improved tolerability compared to other adjuvants. These Al-based …

[HTML][HTML] Fe (III)-Shikonin supramolecular nanomedicines as immunogenic cell death stimulants and multifunctional immunoadjuvants for tumor vaccination

W Feng, W Shi, Y Cui, J Xu, S Liu, H Gao, S Zhu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Immunoadjuvants, as an indispensable component of tumor vaccines, can observably
enhance the magnitude, breadth, and durability of antitumor immunity. However, current …

Biomimetic Gold Nanostructure with a Virus-like Topological Surface for Enhanced Antigen Cross-Presentation and Antitumor Immune Response

Z Wang, T You, C Cai, Q Su, J Cheng… - … Applied Materials & …, 2023 - ACS Publications
The internalization of antigens by dendritic cells (DCs) is the initial critical step for vaccines
to activate the immune response; however, the systemic delivery of antigens into DCs is …

Designing Selenium Nanoadjuvant as Universal Agent for Live‐Killed Virus‐Based Vaccine

B Deng, X He, D Wang, Y Wang, Y Jiang… - Small …, 2023 - Wiley Online Library
Inactivated virus vaccines with whole antigen spectra and good safety are the commonly
used modality for preventing infections. However, the poor immunogenicity greatly limits its …