Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

The lung is repeatedly exposed to inhaled particles and pathogens that are cleared by the
actions of a multi-component innate host defense system. The pulmonary collectins …

Pulmonary surfactant has two distinct functions within the lung: reduction of surface tension
at the air-liquid interface and participation in innate host defense. Both functions are …

The acute inflammatory airway response is characterized by a time-dependent onset
followed by active resolution. Emerging evidence suggests that epithelial cells of the …

The alveolar epithelium is lined by surfactant, a lipoprotein complex that both reduces
surface tension and mediates several innate immune functions including bacterial …

Collectins are a family of innate immune proteins that contain fibrillar collagen-like regions
and globular carbohydrate recognition domains (CRDs). The CRDs of these proteins …

Research over the last decade on the surfactant proteins SP‐A and SP‐D suggests roles
beyond surfactant lipid homeostasis, involving their participation in innate immune defence …

Pulmonary surfactant in bronchoalveolar lavage fluid (BALF) and induced sputum from
adults with stable asthma (n= 36) and healthy controls (n= 12) was analyzed for …

The lung is continuously exposed to inhaled pollutants, microbes and allergens. Therefore,
the pulmonary immune system has to defend against harmful pathogens, while an …

Diagnostic flexible endoscopy for pediatric respiratory diseases is performed in many
centers. Technical advances have resulted in performance of interventional bronchoscopies …