Inflammatory Bowel Disease (IBD) is a multifactorial disorder that conceptually occurs as a
result of altered immune responses to commensal and/or pathogenic gut microbes in …

Inflammatory bowel disease (IBD), including ulcerative colitis, Crohn's disease, and
unclassified IBD, continues to cause significant morbidity. While its incidence is increasing …

Abstract Background and Aims Over 80 monogenic causes of very early onset inflammatory
bowel disease [VEOIBD] have been identified. Prior reports of the natural history of VEOIBD …

The very low-calorie ketogenic diet (VLCKD) has been recognized as a promising dietary
regimen for the treatment of several diseases. Short-chain fatty acids (SCFAs) produced by …

Inborn errors of the intestinal epithelial barrier function as well as the innate and adaptive
mucosal immune responses toward the intestinal microbiota are a group of genetic …

Methods Patients with VEO-IBD diagnosed between 2006 and 2019 were evaluated
retrospectively. The disease phenotypes were classified into ulcerative colitis type (UC-type) …

Allergic disorders target a young population, are increasing in both incidence and
prevalence and are associated with significant disease burden. They result from the …

Background & Aims Asthma and the inflammatory bowel diseases (IBD) each arise through
complex interactions between genetic and environmental factors, and share many …

Background Inflammatory bowel diseases (IBDs) with the subtypes ulcerative colitis (UC)
and Crohn disease (CD), are chronic autoimmune inflammatory disorders of the …

Background Reactive oxygen species can attack and damage almost every molecule found
in living cells, including proteins, carbohydrates, lipids, and DNA. For this reason, their …