Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …
The functional roles of the circRNA/Wnt axis in cancer
CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …
[HTML][HTML] Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling
M Entezari, M Ghanbarirad, A Taheriazam… - Biomedicine & …, 2022 - Elsevier
Among the different kinds of tumors threatening human life, lung cancer is one that is
commonly observed in both males and females. The aggressive behavior of lung cancer …
commonly observed in both males and females. The aggressive behavior of lung cancer …
Association of the epithelial–mesenchymal transition (EMT) with cisplatin resistance
Therapy resistance is a characteristic of cancer cells that significantly reduces the
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …
[HTML][HTML] The metastasizing mechanisms of lung cancer: recent advances and therapeutic challenges
Lung cancer is one of the common malignant tumors that threaten human life with serious
incidence and high mortality. According to the histopathological characteristics, lung cancer …
incidence and high mortality. According to the histopathological characteristics, lung cancer …
LncRNA-BC069792 suppresses tumor progression by targeting KCNQ4 in breast cancer
Y Zhang, X Dong, X Guo, C Li, Y Fan, P Liu, D Yuan… - Molecular cancer, 2023 - Springer
Background Breast cancer is the most common malignant tumor that threatens women's
health. Attention has been paid on the study of long-non-coding RNA (lncRNA) in breast …
health. Attention has been paid on the study of long-non-coding RNA (lncRNA) in breast …
MiRNAs and cancer: key link in diagnosis and therapy
Y Shi, Z Liu, Q Lin, Q Luo, Y Cen, J Li, X Fang, C Gong - Genes, 2021 - mdpi.com
Since the discovery of the first microRNA (miRNA), the exploration of miRNA biology has
come to a new era in recent decades. Monumental studies have proven that miRNAs can be …
come to a new era in recent decades. Monumental studies have proven that miRNAs can be …
Tumor metastasis: Mechanistic insights and therapeutic interventions
M Liu, J Yang, B Xu, X Zhang - MedComm, 2021 - Wiley Online Library
Cancer metastasis is responsible for the vast majority of cancer‐related deaths worldwide. In
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …
Noncoding RNAs link metabolic reprogramming to immune microenvironment in cancers
Y Zhang, Q Mao, Q Xia, J Cheng, Z Huang, Y Li… - Journal of hematology & …, 2021 - Springer
Altered metabolic patterns in tumor cells not only meet their own growth requirements but
also shape an immunosuppressive microenvironment through multiple mechanisms …
also shape an immunosuppressive microenvironment through multiple mechanisms …
Non-coding RNAs and epithelial mesenchymal transition in cancer: molecular mechanisms and clinical implications
H Khanbabaei, S Ebrahimi… - Journal of Experimental …, 2022 - Springer
Epithelial-mesenchymal transition (EMT) is a fundamental process for embryonic
development during which epithelial cells acquire mesenchymal characteristics, and the …
development during which epithelial cells acquire mesenchymal characteristics, and the …