Bacterial sepsis is a major global cause of death. However, the pathophysiology of sepsis
has remained poorly understood. In industrialized nations, Staphylococcus aureus …

BACKGROUND Cytokines and inflammatory mediators are the hallmarks of sepsis.
Extracorporeal cytokine hemoadsorption devices are the newer clinical support system to …

Burn injuries initiate numerous processes such as heat shock response, inflammation and
tissue regeneration. Reliable burn models are needed to elucidate the exact sequence of …

In order to discover novel anti-inflammatory agents, total thirty-seven new resveratrol-based
flavonol derivatives were designed and synthesized. All compounds have been screened for …

Cancer is the primary cause of death in economically developed countries and the second
leading cause in developing countries. Colorectal cancer (CRC) is the third most common …

Background Circulating lipopolysaccharide (LPS) concentrations are often elevated in
patients with sepsis or with various endogenous diseases that are associated with metabolic …

Purpose. Sepsis originates from the host inflammatory response, especially to bacterial
infections, and is considered one of the main causes of death in intensive care units. Various …

Myocardial injury and dysfunction are critical manifestations of sepsis. Previous studies have
reported that liver X receptor (LXR) activation is protective during sepsis. However, whether …

Sepsis, one of the most fatal diseases worldwide, often leads to multiple organ failure,
mainly due to uncontrolled inflammatory responses. Despite accumulating knowledge …

Immunoassays show great potential for the detection of low levels of cytokines, due to their
high sensitivity and excellent specificity. There is a particular demand for biosensors that …