The lungs are affected by illnesses including asthma, chronic obstructive pulmonary
disease, and infections such as influenza and SARS-CoV-2. Physiologically relevant models …

One of the most arduous challenges in tissue engineering is neovascularization, without
which there is a lack of nutrients delivered to a target tissue. Angiogenesis should be …

A comparatively straightforward approach to accomplish more physiological realism in
organ-on-a-chip (OoC) models is through substrate geometry. There is increasing evidence …

Organoids are complex multicellular three-dimensional (3D) in vitro models that are
designed to allow accurate studies of the molecular processes and pathologies of human …

Nanomaterials (NMs) solve specific problems with remarkable results in several industrial
and scientific areas. Among NMs, silver nanoparticles (AgNPs) have been extensively …

Several studies have been conducted to address the potential adverse health risks
attributed to exposure to nanoscale materials. While in vivo studies are fundamental for …

The substantial socioeconomic burden of lung diseases, recently highlighted by the
disastrous impact of the coronavirus disease 2019 (COVID‐19) pandemic, accentuates the …

Prolonged exposure to environmental respirable toxicants can lead to the development and
worsening of severe respiratory diseases such as asthma, chronic obstructive pulmonary …

The gas exchange units of the lung, the alveoli, are mechanically active and undergo cyclic
deformation during breathing. The epithelial cells that line the alveoli contribute to lung …

Due to the current relevance of pulmonary toxicology (with focus upon air pollution and the
inhalation of hazardous materials), it is important to further develop and implement …