Mechanisms in endocrinology: vitamin D and COVID-19

JP Bilezikian, D Bikle, M Hewison… - European journal of …, 2020 - academic.oup.com
The SARS-CoV-2 virus responsible for the COVID-19 pandemic has generated an explosion
of interest both in the mechanisms of infection leading to dissemination and expression of …

[HTML][HTML] Hypercalcemia, hypercalciuria, and kidney stones in long-term studies of vitamin D supplementation: a systematic review and meta-analysis

Z Malihi, Z Wu, AW Stewart, CMM Lawes… - The American journal of …, 2016 - Elsevier
Background: Vitamin D supplementation is increasingly being used in higher doses in
randomized controlled trials (RCTs). However, adverse events from very large annual doses …

Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial

K Amrein, C Schnedl, A Holl, R Riedl, KB Christopher… - Jama, 2014 - jamanetwork.com
Importance Low vitamin D status is linked to increased mortality and morbidity in patients
who are critically ill. It is unknown if this association is causal. Objective To investigate …

Vitamin D insufficiency is prevalent in severe COVID-19

FH Lau, R Majumder, R Torabi, F Saeg, R Hoffman… - MedRxiv, 2020 - medrxiv.org
Background COVID-19 is a major pandemic that has killed more than 196,000 people. The
COVID-19 disease course is strikingly divergent. Approximately 80-85% of patients …

[HTML][HTML] Vitamin D status and its association with season, hospital and sepsis mortality in critical illness

K Amrein, P Zajic, C Schnedl, A Waltensdorfer… - Critical care, 2014 - Springer
Introduction Vitamin D plays a key role in immune function. Deficiency may aggravate the
incidence and outcome of infectious complications in critically ill patients. We aimed to …

[HTML][HTML] Vitamin D deficiency is independently associated with mortality among critically ill patients

RB Moraes, G Friedman, IC Wawrzeniak, LS Marques… - Clinics, 2015 - SciELO Brasil
OBJECTIVE: Studies suggest an association between vitamin D deficiency and
morbidity/mortality in critically ill patients. Several issues remain unexplained, including …

[HTML][HTML] “MATH+” Multi-Modal Hospital Treatment Protocol for COVID-19 Infection: Clinical and Scientific Rationale

P Kory, GU Meduri, J Iglesias, J Varon… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
Abstract In December 2019, coronavirus disease 2019 (COVID-19), a severe respiratory
illness caused by the new coronavirus severe acute respiratory syndrome coronavirus 2 …

Relevance of vitamin D3 in COVID-19 infection

FU Afshan, B Nissar, NA Chowdri, BA Ganai - Gene Reports, 2021 - Elsevier
Abstract SARS-CoV-2 virus, the main culprit for COVID-19 disaster, has triggered a gust of
curiosity both in the mechanism of action of this infection as well as potential risk factors for …

Efficacy of high-dose vitamin D supplementation in the critically ill patients

RM Perron, P Lee - … & Allergy-Drug Targets (Formerly Current …, 2013 - ingentaconnect.com
Vitamin D deficiency and its adverse skeletal sequelae are well recognized in the general
population. Recent observation of high prevalence of low vitamin D states and their …

[HTML][HTML] A pediatric critical care perspective on vitamin D

R Abou-Zahr, SB Kandil - Pediatric research, 2015 - nature.com
The mechanisms of action of vitamin D are the subject of intense investigation. Evidence
now suggests vitamin D affects immune function and cell proliferation, prompting interest in …