Spondyloarthropathies (SpA) include many different forms of inflammatory arthritis and can
affect the spine (axial SpA) and/or peripheral joints (peripheral SpA) with Ankylosing …

Several anti-tumour necrosis factor [TNF] blocking strategies have been evaluated in
patients with Crohn's disease. Compounds that have been tested included the full …

Objectives Here, we present the reported incidence rates of inflammatory bowel disease
(IBD) in patients receiving treatment with secukinumab for psoriasis (PsO), psoriatic arthritis …

The first Food and Drug Administration-(FDA)-approved drugs were small, chemically-
manufactured and highly active molecules with possible off-target effects, followed by …

Paradoxical adverse events (PAEs) have been reported during biological treatment for
chronic immune-mediated diseases. PAEs are defined as the occurrence during biological …

The incidence of esophageal adenocarcinoma (EAC) has increased in recent decades, and
its 5-year survival rate is less than 20%. As a well-established precursor, patients with …

Biotechnological monoclonal antibodies and receptor antagonists capable of targeting
specific inflammatory actors, such as cytokines, cytokines receptors, co-stimulatory …

Spondyloarthritis (SpA) encompasses a heterogeneous group of chronic inflammatory
diseases that can affect both axial and peripheral joints, tendons and entheses. Among the …

As the use of biological therapies expands, the number and diversity of induced
autoimmune disorders should be expected to increase. Paradoxically, for many of these …

Psoriasis and inflammatory bowel disease (IBD) are immune‐mediated diseases occurring
in barrier organs whose main task is to protect the organism from attack. These disorders are …