Assessment of response to neoadjuvant therapy using CT texture analysis in patients with resectable and borderline resectable pancreatic ductal adenocarcinoma

AA Borhani, R Dewan, A Furlan… - American Journal of …, 2020 - Am Roentgen Ray Soc
OBJECTIVE. The goal of this study was to assess the correlation between CT-derived
texture features of pancreatic ductal adenocarcinoma (PDAC) and histologic and …

Potential targets for pancreatic cancer immunotherapeutics

LF Dodson, WG Hawkins, P Goedegebuure - Immunotherapy, 2011 - Taylor & Francis
Pancreatic adenocarcinoma is the fourth leading cause of cancer death with an overall 5-
year survival of less than 5%. As there is ample evidence that pancreatic adenocarcinomas …

Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma

R Chen, DW Dawson, S Pan, NA Ottenhof… - Laboratory …, 2015 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with a dismal
prognosis. However, while most patients die within the first year of diagnosis, very rarely, a …

Vaccinia virus, a promising new therapeutic agent for pancreatic cancer

CA Yaghchi, Z Zhang, G Alusi, NR Lemoine… - Immunotherapy, 2015 - Taylor & Francis
The poor prognosis of pancreatic cancer patients signifies a need for radically new
therapeutic strategies. Tumor-targeted oncolytic viruses have emerged as attractive …

Image-guided hepatopancreatobiliary surgery using near-infrared fluorescent light

FPR Verbeek, JR van der Vorst, BE Schaafsma… - Journal of Hepato-biliary …, 2012 - Springer
Background Improved imaging methods and surgical techniques have created a new era in
hepatopancreatobiliary (HPB) surgery. Despite these developments, visual inspection …

Proteomic analysis of human bile and potential applications for cancer diagnosis

A Farina, JM Dumonceau… - Expert review of proteomics, 2009 - Taylor & Francis
Bile is a body fluid produced by the liver and drained by biliary ducts into the duodenum. It
has two major functions: first, it contains bile acids, which are critical for the digestion of fats …

Preoperative biliary drainage for distal obstruction: the case against revisited

G Garcea, W Chee, SL Ong, GJ Maddern - Pancreas, 2010 - journals.lww.com
Objectives: No conclusive evidence exists confirming the role of preoperative biliary
drainage (PBD) in reversing the physiological disturbances resulting from biliary obstruction …

MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies

M Mimeault, SL Johansson, S Senapati, N Momi… - Cancer letters, 2010 - Elsevier
The present study was undertaken to estimate the therapeutic benefit to down-regulate the
MUC4 mucin for reversing chemoresistance of pancreatic cancer (PC) stem/progenitor cells …

Fluorescence-guided surgery allows for more complete resection of pancreatic cancer, resulting in longer disease-free survival compared with standard surgery in …

CA Metildi, S Kaushal, CR Hardamon… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Negative surgical margins are vital to achieve cure and prolong survival in
patients with pancreatic cancer. We inquired if fluorescence-guided surgery (FGS) could …

CA 19–9 predicts resectability of pancreatic cancer even in jaundiced patients

N Santucci, O Facy, P Ortega-Deballon, JB Lequeu… - Pancreatology, 2018 - Elsevier
Background Surgical resection remains the only curative option for pancreatic
adenocarcinoma. Despite recent improvements in medical imaging, unresectability is still …