[HTML][HTML] miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

[HTML][HTML] Circulating microRNAs as potential cancer biomarkers: the advantage and disadvantage

H Wang, R Peng, J Wang, Z Qin, L Xue - Clinical epigenetics, 2018 - Springer
MicroRNAs are endogenous single-stranded non-coding small RNA molecules that can be
secreted into the circulation and exist stably. They usually exhibit aberrant expression under …

MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance

MA Iqbal, S Arora, G Prakasam, GA Calin… - Molecular aspects of …, 2019 - Elsevier
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …

A study of miRNAs as cornerstone in lung cancer pathogenesis and therapeutic resistance: A focus on signaling pathways interplay

AS Doghish, A Ismail, MA Elrebehy… - … -Research and Practice, 2022 - Elsevier
Lung cancer (LC) is the most common cancer-related death globally, and many efforts have
been made to improve the patient care of LC patients, as well as the development of efficient …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

[HTML][HTML] Progress of exosomes in the diagnosis and treatment of lung cancer

K Xu, C Zhang, T Du, ANA Gabriel, X Wang, X Li… - Biomedicine & …, 2021 - Elsevier
The incidence and mortality of lung cancer account for first place all over the world. Lung
cancer lacks early diagnostic biomarkers; lung cancer patients are usually diagnosed in …

Nucleic acid hybridization on an electrically reconfigurable network of gold-coated magnetic nanoparticles enables microRNA detection in blood

R Tavallaie, J McCarroll, M Le Grand, N Ariotti… - Nature …, 2018 - nature.com
There is intense interest in quantifying the levels of microRNA because of its importance as
a blood-borne biomarker. The challenge has been to develop methods that can monitor …

Recent progress in exosome research: isolation, characterization and clinical applications

X Wang, J Xia, L Yang, J Dai, L He - Cancer Gene Therapy, 2023 - nature.com
Exosomes, a kind of nano-vesicles released by various cell types, carry a variety of “cargos”
including proteins, RNAs, DNAs and lipids. There is substantial evidence that exosomes are …

Overview upon miR-21 in lung cancer: focus on NSCLC

C Bica-Pop, R Cojocneanu-Petric, L Magdo… - Cellular and Molecular …, 2018 - Springer
Considering the high mortality rate encountered in lung cancer, there is a strong need to
explore new biomarkers for early diagnosis and also improved therapeutic targets to …

Extracellular vesicles and their roles in cancer progression

WH Chang, RA Cerione, MA Antonyak - Cancer cell signaling: Methods …, 2021 - Springer
Extracellular vesicles (EVs) produced by cancer cells function as a unique form of
intercellular communication that can promote cell growth and survival, help shape the tumor …