Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part two.

W MacNee - American journal of respiratory and critical care …, 1994 - atsjournals.org
The major difference between patients with COPO who develop edema and those with signs
of" congestive failure" due to ischemic heart disease is that the systemic arteriolar resistance …

Recent insight into therapy of congestive heart failure: focus on ACE inhibition and angiotensin-II antagonism

HP Brunner-La Rocca, G Vaddadi, MD Esler - Journal of the American …, 1999 - jacc.org
One possible intervention to interrupt the deleterious effects of the renin-angiotensin system
is suppression of angiotensin II (Ang II) formation by inhibition of angiotensin-converting …

Effects of enalapril in heart failure: a double blind study of effects on exercise performance, renal function, hormones, and metabolic state.

JG Cleland, HJ Dargie, SG Ball, G Gillen, GP Hodsman… - Heart, 1985 - heart.bmj.com
Several studies have shown symptomatic and haemodynamic improvement after the
introduction of angiotensin converting enzyme inhibitors in patients with heart failure treated …

Comparative hemodynamic and neurohormonal effects of intravenous captopril and digoxin and their combinations in patients with severe heart failure

M Gheorghiade, V Hall, JB Lakier… - Journal of the American …, 1989 - Elsevier
The effects of intravenous captopril and intravenous digoxin given separately and in
combination on rest and exercise hemodynamics were studied in 16 patients with severe …

Severe hypotension after first dose of enalapril in heart failure.

JG Cleland, HJ Dargie, H McAlpine, SG Ball… - Br Med J (Clin Res …, 1985 - bmj.com
The new, long acting converting enzyme inhibitor enalapril was given to 26 patients with
moderate to severe heart failure. In 23 cases the mean systolic blood pressure fell from 120 …

Prejunctional angiotensin II receptors. Facilitation of norepinephrine release in the human forearm.

B Clemson, L Gaul, SS Gubin… - The Journal of …, 1994 - Am Soc Clin Investig
To determine if peripheral angiotensin II (Ang II) prejunctional receptors facilitating NE
release exist in humans, we used [3H] NE kinetic methodology to measure forearm NE …

Effects of captopril on survival in patients with heart failure

TJ Newman, CS Maskin, LG Dennick, JH Meyer… - The American Journal of …, 1988 - Elsevier
Results from a large multicenter study and from the published literature suggest that
captopril can improve survival in patients with advanced heart failure. The survival status of …

Within-patient comparison of effects of different dosages of enalapril on functional capacity and neurohormone levels in patients with chronic heart failure

HP Brunner-La Rocca, D Weilenmann, W Kiowski… - American heart …, 1999 - Elsevier
Background Angiotensin-converting enzyme (ACE) inhibitors are established as first-line
therapy in chronic heart failure (CHF). However, conflicting results exist regarding the dose …

Review of randomized trials of digoxin therapy in patients with chronic heart failure

M Gheorghiade, BJ Zarowitz - The American journal of cardiology, 1992 - Elsevier
Although digitalis glycosides were introduced in the treatment of cardiac maladies> 200
years ago, controversy persists regarding the precise role of digoxin in any multidrug …

Does aspirin attenuate the beneficial effects of angiotensin-converting enzyme inhibition in heart failure?

T Stys, WE Lawson, GC Smaldone… - Archives of internal …, 2000 - jamanetwork.com
Ischemic heart disease is the most common underlying cause of congestive heart failure,
and thus aspirin (acetylsalicylic acid [ASA]) and angiotensin-converting enzyme (ACE) …