[HTML][HTML] The role of inflammation in age-related macular degeneration

W Tan, J Zou, S Yoshida, B Jiang… - International journal of …, 2020 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a blinding eye disease which incidence
gradually increases with age. Inflammation participates in AMD pathogenesis, including …

Recent developments in age-related macular degeneration: a review

WM Al-Zamil, SA Yassin - Clinical interventions in aging, 2017 - Taylor & Francis
Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

[HTML][HTML] HAWK and HARRIER: phase 3, multicenter, randomized, double-masked trials of brolucizumab for neovascular age-related macular degeneration

PU Dugel, A Koh, Y Ogura, GJ Jaffe, U Schmidt-Erfurth… - Ophthalmology, 2020 - Elsevier
Purpose Two similarly designed phase 3 trials (HAWK and HARRIER) compared
brolucizumab, a single-chain antibody fragment that inhibits vascular endothelial growth …

Vitamin D and ocular diseases: a systematic review

HN Chan, XJ Zhang, XT Ling, CHT Bui… - International journal of …, 2022 - mdpi.com
The contributory roles of vitamin D in ocular and visual health have long been discussed,
with numerous studies pointing to the adverse effects of vitamin D deficiency. In this paper …

Age‐related macular degeneration: new paradigms for treatment and management of AMD

LF Hernández-Zimbrón… - Oxidative medicine …, 2018 - Wiley Online Library
Age‐related macular degeneration (AMD) is a well‐characterized and extensively studied
disease. It is currently considered the leading cause of visual disability among patients over …

Clinical applications of fundus autofluorescence in retinal disease

M Yung, MA Klufas, D Sarraf - International journal of retina and vitreous, 2016 - Springer
Fundus autofluorescence (FAF) is a non-invasive retinal imaging modality used in clinical
practice to provide a density map of lipofuscin, the predominant ocular fluorophore, in the …

Genetics of age-related macular degeneration (AMD)

MM DeAngelis, LA Owen, MA Morrison… - Human molecular …, 2017 - academic.oup.com
Age-related macular degeneration (AMD) is a progressive blinding disease and represents
the leading cause of visual impairment in the aging population. AMD affects central vision …

Platinum nanozymes counteract photoreceptor degeneration and retina inflammation in a light-damage model of age-related macular degeneration

S Cupini, S Di Marco, L Boselli, A Cavalli, G Tarricone… - ACS …, 2023 - ACS Publications
Degeneration of photoreceptors in age-related macular degeneration (AMD) is associated
with oxidative stress due to the intense aerobic metabolism of rods and cones that if not …

Metabolomics in the study of retinal health and disease

I Laíns, M Gantner, S Murinello, JA Lasky-Su… - Progress in retinal and …, 2019 - Elsevier
Metabolomics is the qualitative and quantitative assessment of the metabolites (small
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …

Treatment regimens for administration of anti‐vascular endothelial growth factor agents for neovascular age‐related macular degeneration

E Li, S Donati, KB Lindsley… - Cochrane Database …, 2020 - cochranelibrary.com
Background Age‐related macular degeneration (AMD) is one of the leading causes of
permanent blindness worldwide. The current mainstay of treatment for neovascular AMD …