Biodegradability and ecotoxicitiy of tramadol, ranitidine, and their photoderivatives in the aquatic environment

M Bergheim, R Gieré, K Kümmerer - Environmental Science and Pollution …, 2012 - Springer
Purpose This study was designed to assess the fate and the overall potential impacts of the
widely prescribed drugs ranitidine and tramadol after their introduction into the aquatic …

Preparation of end-capped pH-sensitive mesoporous silica nanocarriers for on-demand drug delivery

AF Moreira, VM Gaspar, EC Costa… - European Journal of …, 2014 - Elsevier
Nanocarriers with a pH responsive behavior are receiving an ever growing attention due to
their potential for promoting on-demand drug release and thus increase the therapeutic …

Oxidation kinetics of cyclophosphamide and methotrexate by ozone in drinking water

A Garcia-Ac, R Broséus, S Vincent, B Barbeau… - Chemosphere, 2010 - Elsevier
This study investigates the aqueous degradation by ozone of two target cytostatic drugs,
cyclophosphamide and methotrexate. A column switching technique for on-line solid phase …

Combined environmental risk assessment for 5‐fluorouracil and capecitabine in Europe

JO Straub - Integrated Environmental Assessment and …, 2010 - Wiley Online Library
An environmental risk assessment (ERA) was made for the old cytostatic active
pharmaceutical ingredient 5‐fluorouracil (5‐FU) and for capecitabine (CAP), which is a …

Removal of cytostatic drugs by AOPs: A review of applied processes in the context of green technology

A Pieczyńska, A Fiszka Borzyszkowska… - Critical Reviews in …, 2017 - Taylor & Francis
For decades, cytostatic drugs have been widely used in chemotherapy. However, many of
these chemicals are classified as carcinogenic, mutagenic and teratogenic compounds …

Ecotoxicological assessment of the anticancer drug cisplatin in the polychaete Nereis diversicolor

TG Fonseca, MB Morais, T Rocha, DMS Abessa… - Science of the total …, 2017 - Elsevier
Anticancer drugs are designed to inhibit tumor cell proliferation by interacting with DNA and
altering cellular growth factors. When released into the waterbodies of municipal and …

[HTML][HTML] Translating antibiotic prescribing into antibiotic resistance in the environment: A hazard characterisation case study

AC Singer, Q Xu, VDJ Keller - PLoS One, 2019 - journals.plos.org
The environment receives antibiotics through a combination of direct application (eg,
aquaculture and fruit production), as well as indirect release through pharmaceutical …

Evaluation of toxic effects of platinum-based antineoplastic drugs (cisplatin, carboplatin and oxaliplatin) on green alga Chlorella vulgaris

S Dehghanpour, HR Pourzamani, MM Amin… - Aquatic Toxicology, 2020 - Elsevier
Platinum-based antineoplastic drugs (PBADs) enter the environment via hospital and
municipal wastes as reactive and highly toxic molecules. Chlorella vulgaris is a freshwater …

Cytostatic drugs in environmental samples: An update on the extraction and determination procedures

S Santana-Viera, S Montesdeoca-Esponda… - TrAC Trends in …, 2016 - Elsevier
Antineoplastic or cytostatic compounds are used to fight cancer. They are a broad group of
organic compounds, possessing a diverse range of physico-chemical characteristics. Given …

New insights into transformation pathways of a mixture of cytostatic drugs using Polyester-TiO2 films: Identification of intermediates and toxicity assessment

E Evgenidou, A Ofrydopoulou… - Science of the Total …, 2020 - Elsevier
The photocatalytic activity of two bio-based polymer photocatalysts [poly (ethylene
terephthalate)-TiO 2 (PET-TiO 2) and poly (L-lactic acid)-graphene oxide-TiO 2 (PLLA-GO …