Pulmonary hypertension

A Mocumbi, M Humbert, A Saxena, ZC Jing… - Nature Reviews …, 2024 - nature.com
Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to
elevated pressures within the pulmonary arteries. Five main groups of pulmonary …

[HTML][HTML] Global effect of modifiable risk factors on cardiovascular disease and mortality

Global Cardiovascular Risk … - New England Journal of …, 2023 - Mass Medical Soc
Background Five modifiable risk factors are associated with cardiovascular disease and
death from any cause. Studies using individual-level data to evaluate the regional and sex …

Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis

J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …

Aldosterone synthase inhibition with lorundrostat for uncontrolled hypertension: the target-HTN randomized clinical trial

LJ Laffin, D Rodman, JM Luther, A Vaidya, MR Weir… - Jama, 2023 - jamanetwork.com
Importance Excess aldosterone production contributes to hypertension in both classical
hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …

[HTML][HTML] Global, regional, and national burden of cardiovascular diseases in youths and young adults aged 15–39 years in 204 countries/territories, 1990–2019: a …

J Sun, Y Qiao, M Zhao, CG Magnussen, B Xi - BMC medicine, 2023 - Springer
Background Understanding the temporal trends in the burden of overall and type-specific
cardiovascular diseases (CVDs) in youths and young adults and its attributable risk factors is …

[HTML][HTML] Association between triglyceride glucose-body mass index and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a …

Y Cheng, Z Fang, X Zhang, Y Wen, J Lu, S He… - Cardiovascular …, 2023 - Springer
Background The triglyceride glucose-body mass index (TyG-BMI index) has been
considered a reliable surrogate measure of insulin resistance; however, its ability to predict …

[HTML][HTML] 2023: The year in cardiovascular disease–the year of new and prospective lipid lowering therapies. Can we render dyslipidemia a rare disease by 2024?

M Banach, S Surma, PP Toth - Archives of Medical Science: AMS, 2023 - ncbi.nlm.nih.gov
In 2023 there are still even 75% of patients over the target of low-density lipoprotein
cholesterol (LDL-C), and hypercholesterolemia is the most common and the worst monitored …

[HTML][HTML] Association between non-insulin-based insulin resistance indices and cardiovascular events in patients undergoing percutaneous coronary intervention: a …

Z Zhang, L Zhao, Y Lu, X Meng, X Zhou - Cardiovascular Diabetology, 2023 - Springer
Background Insulin resistance (IR) has been confirmed that getting involved in the
pathophysiological process of cardiovascular diseases (CVD). Recently, increasing …

[HTML][HTML] A look to the past–what has had the biggest impact on lipids in the last four decades? A personal perspective

M Banach, S Surma - Archives of Medical Science: AMS, 2023 - ncbi.nlm.nih.gov
We live in interesting times, when we finally have the possibility of effective treatment of
patients with lipid disorders, and in fact with numerous effective drugs available, it should be …

Fulminant mpox as an AIDS-defining condition: useful or stigmatising?

I Núñez, SI Valdés-Ferrer - The Lancet, 2023 - thelancet.com
Unfortunately, the CRHCP trial did not evaluate process or implementation outcomes to aid
our assessment of its scalability in rural China and elsewhere in the world. Despite …