Magnetic resonance imaging-guided radiation therapy (MRIgRT) has improved soft tissue
contrast over computed tomography (CT) based image-guided RT. Superior visualization of …

Drug delivery platforms have gracefully emerged as an indispensable component of novel
cancer chemotherapy, bestowing targeted drug distribution, elevating therapeutic effects …

The extracellular pH (pHe) of solid tumors is often acidic, as a consequence of the Warburg
effect, and an altered metabolic state is often associated with malignancy. It has been shown …

Image guided nose-to-brain drug delivery provides a non-invasive way to monitor drug
delivered to the brain, and the intranasal administration could increase effective dose via …

Imaging pHe of the tumor microenvironment has paramount importance for characterizing
aggressive, invasive tumors, as well as therapeutic responses. Here, a robust approach to …

Chemical exchange saturation transfer (CEST) MRI is a molecular imaging tool that provides
physiological information about tissues, making it an invaluable tool for disease diagnosis …

Background: Noninvasive imaging of molecular alterations after intracerebral hemorrhage
(ICH) could provide valuable information to guide and monitor treatments. Chemical …

Treating glioblastoma and monitoring treatment response non-invasively remain
challenging. Here, we developed a robust approach using a drug-loaded liposomal …

Amide proton transfer (APT) magnetic resonance imaging (MRI) is an important molecular
imaging technique at the protein level in tissue. Neurodegenerative diseases have a high …

The fluid transport of cerebrospinal fluid (CSF) and interstitial fluid in surrounding tissues
plays an important role in the drainage pathway that facilitates waste clearance from the …