Targeting vascular calcification in chronic kidney disease
Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …
End-stage renal disease, inflammation and cardiovascular outcomes
L Dai, E Golembiewska, B Lindholm… - Expanded …, 2017 - karger.com
Despite marked improvements in renal replacement therapy during the last 30 years, the
age-adjusted mortality rate in end-stage renal disease (ESRD) patients is still unacceptably …
age-adjusted mortality rate in end-stage renal disease (ESRD) patients is still unacceptably …
Circulating endotoxemia: a novel factor in systemic inflammation and cardiovascular disease in chronic kidney disease
CW McIntyre, LEA Harrison, MT Eldehni… - Clinical Journal of the …, 2011 - journals.lww.com
Results Circulating endotoxemia was most notable in those with the highest CV disease
burden (increasing with CKD stage), and a sharp increase was observed after initiation of …
burden (increasing with CKD stage), and a sharp increase was observed after initiation of …
[HTML][HTML] Fibroblast growth factor 23 is not associated with and does not induce arterial calcification
Elevated fibroblast growth factor 23 (FGF23) is associated with cardiovascular disease in
patients with chronic kidney disease. As a potential mediating mechanism, FGF23 induces …
patients with chronic kidney disease. As a potential mediating mechanism, FGF23 induces …
Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle?
P Stenvinkel, J Jesu, J Axelsson… - Clinical journal of the …, 2008 - journals.lww.com
Premature cardiovascular disease (CVD), including stroke, peripheral vascular disease,
sudden death, coronary artery disease, and congestive heart failure, is a notorious problem …
sudden death, coronary artery disease, and congestive heart failure, is a notorious problem …
Hemodialysis-induced repetitive myocardial injury results in global and segmental reduction in systolic cardiac function
Background and objectives: Hemodialysis (HD)-induced regional wall motion abnormalities
(RWMAs) are common in HD patients and driven by ischemia. In nondialysis patients …
(RWMAs) are common in HD patients and driven by ischemia. In nondialysis patients …
Progressive vascular calcification over 2 years is associated with arterial stiffening and increased mortality in patients with stages 4 and 5 chronic kidney disease
MK Sigrist, MW Taal, P Bungay… - Clinical Journal of the …, 2007 - journals.lww.com
Background and objectives: Vascular calcification is increasingly recognized as an
important component of cardiovascular disease in chronic kidney disease. The objective of …
important component of cardiovascular disease in chronic kidney disease. The objective of …
Fibroblast growth factor-23 (FGF-23) is independently correlated to aortic calcification in haemodialysis patients
MM Nasrallah, AR El-Shehaby… - Nephrology Dialysis …, 2010 - academic.oup.com
Background. Vascular calcification has detrimental consequences on chronic kidney
disease (CKD) patients, yet its pathogenesis is not fully understood. Fibroblast growth factor …
disease (CKD) patients, yet its pathogenesis is not fully understood. Fibroblast growth factor …
Calcification in atherosclerosis
N Alexopoulos, P Raggi - Nature Reviews Cardiology, 2009 - nature.com
Coronary calcification has long been known to occur as a part of the atherosclerotic process,
although whether it is a marker of plaque stability or instability is still a topic of considerable …
although whether it is a marker of plaque stability or instability is still a topic of considerable …
Associations between vascular calcification, arterial stiffness and bone mineral density in chronic kidney disease
ND Toussaint, KK Lau, BJ Strauss… - Nephrology Dialysis …, 2008 - academic.oup.com
Background. Vascular calcification (VC) and arterial stiffness are major contributors to
cardiovascular (CV) disease in chronic kidney disease (CKD). Both are independent …
cardiovascular (CV) disease in chronic kidney disease (CKD). Both are independent …