The role of fibroblast growth factor 23 in inflammation and anemia

B Czaya, C Faul - International journal of molecular sciences, 2019 - mdpi.com
In patients with chronic kidney disease (CKD), adverse outcomes such as systemic
inflammation and anemia are contributing pathologies which increase the risks for …

An update on phosphate binders for the treatment of hyperphosphatemia in chronic kidney disease patients on dialysis: a review of safety profiles

H Ogata, A Takeshima, H Ito - Expert opinion on drug safety, 2022 - Taylor & Francis
Introduction Hyperphosphatemia is an inevitable complication for patients undergoing
dialysis, as is the resulting need for treatment with phosphate binders. Currently, various …

[HTML][HTML] Ferric citrate reduces fibroblast growth factor 23 levels and improves renal and cardiac function in a mouse model of chronic kidney disease

C Francis, G Courbon, C Gerber, S Neuburg, X Wang… - Kidney international, 2019 - Elsevier
Iron deficiency, anemia, hyperphosphatemia, and increased fibroblast growth factor 23
(FGF23) are common and interrelated complications of chronic kidney disease (CKD) that …

Effects of sucroferric oxyhydroxide and sevelamer carbonate on chronic kidney disease–mineral bone disorder parameters in dialysis patients

M Ketteler, SM Sprague, AC Covic… - Nephrology Dialysis …, 2019 - academic.oup.com
Background Treatment of hyperphosphataemia is the primary goal of chronic kidney disease–
mineral and bone disorder (CKD-MBD) management. This post hoc analysis of a …

Effect of ferric citrate on serum phosphate and fibroblast growth factor 23 among patients with nondialysis-dependent chronic kidney disease: path analyses

GA Block, PE Pergola, S Fishbane… - Nephrology Dialysis …, 2019 - academic.oup.com
Background Among patients with nondialysis-dependent chronic kidney disease (NDD-
CKD) and iron-deficiency anemia (IDA), ferric citrate increases hemoglobin and iron …

Regulation of fibroblast growth factor 23 by iron, EPO, and HIF

JA Wheeler, EL Clinkenbeard - Current molecular biology reports, 2019 - Springer
Abstract Purpose of Review Fibroblast growth factor-23 (FGF23) is the key hormone
produced in bone critical for phosphate homeostasis. Elevated serum phosphorus and 1, 25 …

Phosphate wasting disorders in adults

G Marcucci, L Masi, S Ferrarì, D Haffner… - Osteoporosis …, 2018 - Springer
A cause of hypophosphatemia is phosphate wasting disorders. Knowledge concerning
mechanisms involved in phosphate wasting disorders has greatly increased in the last …

Ferric citrate for the treatment of hyperphosphatemia and anemia in patients with chronic kidney disease: a meta-analysis of randomized clinical trials

L Li, X Zheng, J Deng, J Zhou, J Ou, T Hong - Renal Failure, 2022 - Taylor & Francis
Background Hyperphosphatemia and anemia, which are common complications of chronic
kidney disease (CKD), can independently contribute to cardiovascular events. Several …

New concepts in regulation and function of the FGF23

S Dastghaib, F Koohpeyma, M Shams, F Saki… - Clinical and …, 2023 - Springer
In comparison to the regulation of calcium homeostasis, which has been widely studied over
the last several decades, phosphate homeostasis is little understood. The parathyroid …

Crosstalk between fibroblast growth factor 23, iron, erythropoietin, and inflammation in kidney disease

JL Babitt, D Sitara - Current opinion in nephrology and …, 2019 - journals.lww.com
Regulation of FGF23 is complex and involves many bone and renal factors. More recently,
erythropoietin, iron deficiency, and inflammation have been also shown to affect FGF23 …