Dynamic nuclear polarization for sensitivity enhancement in biomolecular solid-state NMR
T Biedenbänder, V Aladin, S Saeidpour… - Chemical …, 2022 - ACS Publications
Solid-state NMR with magic-angle spinning (MAS) is an important method in structural
biology. While NMR can provide invaluable information about local geometry on an atomic …
biology. While NMR can provide invaluable information about local geometry on an atomic …
Biomolecular and biological applications of solid-state NMR with dynamic nuclear polarization enhancement
WY Chow, G De Paëpe, S Hediger - Chemical Reviews, 2022 - ACS Publications
Solid-state NMR spectroscopy (ssNMR) with magic-angle spinning (MAS) enables the
investigation of biological systems within their native context, such as lipid membranes, viral …
investigation of biological systems within their native context, such as lipid membranes, viral …
From angstroms to nanometers: measuring interatomic distances by solid-state NMR
Internuclear distances represent one of the main structural constraints in molecular structure
determination using solid-state NMR spectroscopy, complementing chemical shifts and …
determination using solid-state NMR spectroscopy, complementing chemical shifts and …
Highly bioresistant, hydrophilic and rigidly linked trityl-nitroxide biradicals for cellular high-field dynamic nuclear polarization
R Yao, D Beriashvili, W Zhang, S Li, A Safeer… - Chemical …, 2022 - pubs.rsc.org
Cellular dynamic nuclear polarization (DNP) has been an effective means of overcoming the
intrinsic sensitivity limitations of solid-state nuclear magnetic resonance (ssNMR) …
intrinsic sensitivity limitations of solid-state nuclear magnetic resonance (ssNMR) …
[HTML][HTML] Understanding molecular mechanisms of biologics drug delivery and stability from NMR spectroscopy
Protein therapeutics carry inherent limitations of membrane impermeability and structural
instability, despite their predominant role in the modern pharmaceutical market. Effective …
instability, despite their predominant role in the modern pharmaceutical market. Effective …
SARS-CoV-2 envelope protein forms clustered pentamers in lipid bilayers
The SARS-CoV-2 envelope (E) protein is a viroporin associated with the acute respiratory
symptoms of COVID-19. E forms cation-selective ion channels that assemble in the lipid …
symptoms of COVID-19. E forms cation-selective ion channels that assemble in the lipid …
Direct observation of cholesterol dimers and tetramers in lipid bilayers
Cholesterol is a ubiquitous component of mammalian cell membranes and affects
membrane protein function. Although cholesterol-mediated formation of ordered membrane …
membrane protein function. Although cholesterol-mediated formation of ordered membrane …
Protein amphipathic helix insertion: A mechanism to induce membrane fission
MA Zhukovsky, A Filograna, A Luini, D Corda… - Frontiers in cell and …, 2019 - frontiersin.org
One of the fundamental features of biomembranes is the ability to fuse or to separate. These
processes called respectively membrane fusion and fission are central in the homeostasis of …
processes called respectively membrane fusion and fission are central in the homeostasis of …
Characterization of dielectric properties and their impact on MAS-DNP NMR applications
The dielectric properties of materials play a crucial role in the propagation and absorption of
microwave beams employed in Magic Angle Spinning− Dynamic Nuclear Polarization (MAS …
microwave beams employed in Magic Angle Spinning− Dynamic Nuclear Polarization (MAS …
Substitution-type luminescent MOF sensor with built-in capturer for selective cholesterol detection in blood serum
M Gong, J Yang, Y Li, Q Zhuang, J Gu - Journal of Materials Chemistry …, 2019 - pubs.rsc.org
The development of an effective strategy for the accurate detection of cholesterol in human
serum is of great significance. Herein, a novel luminescent metal–organic framework …
serum is of great significance. Herein, a novel luminescent metal–organic framework …