Oxytocin attenuates phencyclidine hyperactivity and increases social interaction and nucleus accumben dopamine release in rats
S Kohli, MV King, S Williams, A Edwards… - …, 2019 - nature.com
The pituitary neuropeptide oxytocin promotes social behavior, and is a potential adjunct
therapy for social deficits in schizophrenia and autism. Oxytocin may mediate pro-social …
therapy for social deficits in schizophrenia and autism. Oxytocin may mediate pro-social …
Effect of early life social adversity on drug abuse vulnerability: Focus on corticotropin-releasing factor and oxytocin
MT Bardo, LR Hammerslag, SG Malone - Neuropharmacology, 2021 - Elsevier
Early life adversity can set the trajectory for later psychiatric disorders, including substance
use disorders. There are a host of neurobiological factors that may play a role in the …
use disorders. There are a host of neurobiological factors that may play a role in the …
Oxytocinergic manipulations in corticolimbic circuit differentially affect fear acquisition and extinction
N Lahoud, M Maroun - Psychoneuroendocrinology, 2013 - Elsevier
The oxytocinergic system promotes social behavior and reduces anxiety. The significant
roles and functional interactions of the medial prefrontal cortex and the amygdala in the …
roles and functional interactions of the medial prefrontal cortex and the amygdala in the …
The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats
The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …
Peripheral oxytocin administration reduces ethanol consumption in rats
K MacFadyen, R Loveless, B DeLucca… - Pharmacology …, 2016 - Elsevier
The neuropeptide oxytocin interacts with mesolimbic dopamine neurons to mediate reward
associated with filial behaviors, but also other rewarding behaviors such as eating or taking …
associated with filial behaviors, but also other rewarding behaviors such as eating or taking …
Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine‐seeking behaviour in rats
The psychostimulant methamphetamine (METH) is an addictive illicit drug. Systemic
administration of the neuropeptide oxytocin modulates METH‐related reward and METH …
administration of the neuropeptide oxytocin modulates METH‐related reward and METH …
The effect of chronic oxytocin treatment during abstinence from methamphetamine self-administration on incubation of craving, reinstatement, and anxiety
Methamphetamine (METH) abuse is characterised by chronic relapse and anxiety, for which
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …
there are no effective pharmacotherapies. Acute treatment with the neuropeptide oxytocin …
Neural mechanisms underlying incubation of methamphetamine craving: a mini-review
RD Altshuler, H Lin, X Li - Pharmacology Biochemistry and Behavior, 2020 - Elsevier
Cue-induced drug craving and seeking progressively increases during abstinence. This
“incubation of drug craving” phenomenon has been observed in both laboratory animals …
“incubation of drug craving” phenomenon has been observed in both laboratory animals …
Oxytocin regulates changes of extracellular glutamate and GABA levels induced by methamphetamine in the mouse brain
Oxytocin (OT), a neurohypophyseal neuropeptide, affects adaptive processes of the central
nervous system. In the present study, we investigated the effects of OT on extracellular levels …
nervous system. In the present study, we investigated the effects of OT on extracellular levels …
The impact of early life stress on the central oxytocin system and susceptibility for drug addiction: Applicability of oxytocin as a pharmacotherapy
Early life trauma is strongly associated with an increased vulnerability to abuse illicit drugs
and the impairment of neural development. This includes alterations to the development of …
and the impairment of neural development. This includes alterations to the development of …