Oxytocin directly administered into the nucleus accumbens core or subthalamic nucleus attenuates methamphetamine-induced conditioned place preference
Accumulating evidence indicates that the neuropeptide oxytocin (OXY) may modulate
reward-related behavioural responses to methamphetamine (METH) administration. Limited …
reward-related behavioural responses to methamphetamine (METH) administration. Limited …
Oxytocin signaling in the treatment of drug addiction: Therapeutic opportunities and challenges
X Che, J Cai, Y Liu, T Xu, J Yang, C Wu - Pharmacology & therapeutics, 2021 - Elsevier
Drug addiction is one of the leading causes of mortality worldwide. Despite great advances
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …
were achieved in understanding the neurobiology of drug addiction, the therapeutic options …
Role of oxytocin and vasopressin in neuropsychiatric disorders: therapeutic potential of agonists and antagonists
Oxytocin (OT) and vasopressin (AVP) are hypothalamic neuropeptides classically
associated with their regulatory role in reproduction, water homeostasis, and social …
associated with their regulatory role in reproduction, water homeostasis, and social …
Stress, sex, and addiction: potential roles of corticotropin-releasing factor, oxytocin, and arginine-vasopressin
V Bisagno, JL Cadet - Behavioural pharmacology, 2014 - journals.lww.com
Stress sensitivity and sex are predictive factors for the development of neuropsychiatric
disorders. Life stresses are not only risk factors for the development of addiction but also are …
disorders. Life stresses are not only risk factors for the development of addiction but also are …
A role for oxytocin in the etiology and treatment of schizophrenia
ME Rich, HK Caldwell - Frontiers in endocrinology, 2015 - frontiersin.org
Schizophrenia is a chronic debilitating neuropsychiatric disorder estimated to affect 51
million people worldwide. Several symptom domains characterize schizophrenia, including …
million people worldwide. Several symptom domains characterize schizophrenia, including …
Oxytocin prevents the increase of cocaine-related responses produced by social defeat
The neuropeptide oxytocin (OXT) plays a critical role in the regulation of social and
emotional behaviors. OXT plays a role in stress response and in drug reward, but to date no …
emotional behaviors. OXT plays a role in stress response and in drug reward, but to date no …
The nonpeptide oxytocin receptor agonist WAY 267,464: Receptor‐binding profile, prosocial effects and distribution of c‐Fos expression in adolescent rats
C Hicks, W Jorgensen, C Brown… - Journal of …, 2012 - Wiley Online Library
Previous research suggests that the nonpeptide oxytocin receptor (OTR) agonist WAY
267,464 may only partly mimic the effects of oxytocin in rodents. The present study further …
267,464 may only partly mimic the effects of oxytocin in rodents. The present study further …
Oxytocin, tolerance, and the dark side of addiction
CA Pedersen - International review of neurobiology, 2017 - Elsevier
Substance use disorders blight the lives of millions of people and inflict a heavy financial
burden on society. There is a compelling need for new pharmacological treatments as …
burden on society. There is a compelling need for new pharmacological treatments as …
Regionally specific effects of oxytocin on reinstatement of cocaine seeking in male and female rats
Background Oxytocin reduces cued reinstatement of cocaine seeking in male and female
rats, but the underlying neurobiology has not been uncovered. The majority of effort on this …
rats, but the underlying neurobiology has not been uncovered. The majority of effort on this …
The neurocircuitry involved in oxytocin modulation of methamphetamine addiction
SJ Baracz, JL Cornish - Frontiers in neuroendocrinology, 2016 - Elsevier
The role of oxytocin in attenuating the abuse of licit and illicit drugs, including the
psychostimulant methamphetamine, has been examined with increased ferocity in recent …
psychostimulant methamphetamine, has been examined with increased ferocity in recent …