Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype
The major challenge in treating methamphetamine addicts is the maintenance of a drug free-
state since they experience negative emotional symptoms during abstinence, which may …
state since they experience negative emotional symptoms during abstinence, which may …
Oxytocin and addiction: potential glutamatergic mechanisms
Recently, oxytocin (OXT) has been investigated for its potential therapeutic role in addiction.
OXT has been found to diminish various drug-seeking and drug-induced behaviors …
OXT has been found to diminish various drug-seeking and drug-induced behaviors …
Adolescent pre‐treatment with oxytocin protects against adult methamphetamine‐seeking behavior in female rats
The neuropeptide oxytocin (OT), given acutely, reduces self‐administration of the
psychostimulant drug methamphetamine (METH). Additionally, chronic OT administration to …
psychostimulant drug methamphetamine (METH). Additionally, chronic OT administration to …
Chronic methamphetamine treatment induces oxytocin receptor up-regulation in the amygdala and hypothalamus via an adenosine A2A receptor-independent …
P Zanos, SR Wright, P Georgiou, JH Yoo… - Pharmacology …, 2014 - Elsevier
There is mounting evidence that the neuropeptide oxytocin is a possible candidate for the
treatment of drug addiction. Oxytocin was shown to reduce methamphetamine self …
treatment of drug addiction. Oxytocin was shown to reduce methamphetamine self …
The role of oxytocin and vasopressin in drug-induced reward—implications for social and non-social factors
O Wronikowska-Denysiuk, W Mrozek, B Budzyńska - Biomolecules, 2023 - mdpi.com
Drug abuse is a worldwide problem that leads to negative physical, mental, and economic
consequences. Although pharmacological strategies for drug addiction management have …
consequences. Although pharmacological strategies for drug addiction management have …
[HTML][HTML] Compulsive methamphetamine taking and abstinence in the presence of adverse consequences: Epigenetic and transcriptional consequences in the rat brain
JL Cadet, R Patel, S Jayanthi - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
Methamphetamine addiction is characterized by compulsive binges of drug intake despite
adverse life consequences. A model of methamphetamine self-administration that includes …
adverse life consequences. A model of methamphetamine self-administration that includes …
Complexity of oxytocin׳ s effects in a chronic cocaine dependent population
MR Lee, M Glassman, B King-Casas, DL Kelly… - European …, 2014 - Elsevier
Behavioral and neuroplastic changes occurring in the development of addiction parallel
those that occur in social bonding. This has led to speculation that drugs of abuse co-opt …
those that occur in social bonding. This has led to speculation that drugs of abuse co-opt …
Sign tracking predicts cue-induced but not drug-primed reinstatement to methamphetamine seeking in rats: Effects of oxytocin treatment
Background: The incentive sensitisation theory of addiction posits that drug-associated
stimuli become imbued with incentive motivational properties, driving pathological drug …
stimuli become imbued with incentive motivational properties, driving pathological drug …
Oxytocin: parallel processing in the social brain?
G Dölen - Journal of neuroendocrinology, 2015 - Wiley Online Library
Early studies attempting to disentangle the network complexity of the brain exploited the
accessibility of sensory receptive fields to reveal circuits made up of synapses connected …
accessibility of sensory receptive fields to reveal circuits made up of synapses connected …
Oxytocin increases physiological linkage during group therapy for methamphetamine use disorder: a randomized clinical trial
Patients and psychotherapists often exhibit behavioral, psychological, and physiological
similarity. Here, we test whether oxytocin—a neuropeptide that can enhance expressivity …
similarity. Here, we test whether oxytocin—a neuropeptide that can enhance expressivity …