Oxytocin in the amygdala and not the prefrontal cortex enhances fear and impairs extinction in the juvenile rat

M Kritman, N Lahoud, M Maroun - Neurobiology of learning and memory, 2017 - Elsevier
A growing body of evidence suggests that the hypothalamic neuropeptide oxytocin (OT),
aside from its central role in the regulation of social behavior, reduces fear and anxiety. The …

The intersection of empathy and addiction

SS Cox, CM Reichel - Pharmacology biochemistry and behavior, 2023 - Elsevier
Empathy, the ability to perceive the affective state of another, is a complex process that is
integral to many of the prosocial behaviors expressed in humans and across the animal …

Effects of oxytocin on nicotine withdrawal in rats

KE Manbeck, D Shelley, CE Schmidt… - … Biochemistry and Behavior, 2014 - Elsevier
Abstract Development of medications that attenuate symptoms of nicotine withdrawal may
be useful for facilitating smoking cessation. The neuropeptide oxytocin (OXY) decreases …

The interplay of childhood trauma, oxytocin, and impulsivity in predicting the onset of methamphetamine use

HM Chang, C Chen, ML Lu, S Jou, VHJ Santos… - Child Abuse & …, 2024 - Elsevier
Background Childhood trauma is associated with substance use disorders, including
methamphetamine use disorder (MUD). Oxytocin, involved in social bonding, stress …

[图书][B] Psychostimulants

GF Koob, MA Arends, ML McCracken, M Le Moal - 2020 - books.google.com
A current survey and synthesis of the most important findings in our understanding of the
neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction …

Oxytocin reduces cigarette consumption in daily smokers

K Van Hedger, MJ Kushner, R Lee… - Nicotine and Tobacco …, 2019 - academic.oup.com
Introduction Despite widespread knowledge of the dangers of cigarette consumption,
smoking continues to be a public health concern. One compound that has shown potential …

Effect of social housing and oxytocin on the motivation to self-administer methamphetamine in female rats

C Westenbroek, AN Perry, L Jagannathan… - Physiology & …, 2019 - Elsevier
Social housing has been shown to attenuate the motivation for cocaine in female, but not
male rats. Here we investigate the potential mechanisms mediating the effect of social …

Oxytocin as a potential mediator and modulator of drug addiction

Z Sarnyai - Addiction Biology, 2011 - researchonline.jcu.edu.au
[Extract] Oxytocin, a nine amino acid neuropeptide, first discovered by Sir Heury Dale in
1906, is a potent modulator of a variety of brain functions including emotions, mood, social …

The multidimensional therapeutic potential of targeting the brain oxytocin system for the treatment of substance use disorders

MT Bowen, ID Neumann - Behavioral Pharmacology of Neuropeptides …, 2018 - Springer
The neuropeptide oxytocin is released both into the blood and within the brain in response
to reproductive stimuli, such as birth, suckling and sex, but also in response to social …

Effects of intranasal oxytocin on stress-induced cigarette craving in daily smokers

K Van Hedger, AK Bershad, R Lee… - Nicotine and Tobacco …, 2020 - academic.oup.com
Background Cigarette smoking is a well-known public health concern, and there is an urgent
need to develop new treatments to reduce smoking or facilitate abstinence. One factor that is …