This review is aimed at providing readers with a comprehensive reference article about the
distribution and function of P2 receptors in all the organs, tissues, and cells in the body …

P2Y2 receptor agonists, like UTP and ATP, stimulate mucin secretion from goblet cells in
vitro. Therefore, mucin stimulants could be good candidates for the treatment of dry eye …

purpose. Because purinoceptor P2Y 2 receptor agonists elicit increases in net Cl, fluid
transport, and glycoprotein release onto the ocular surface, they are candidates for treatment …

The purpose of the present study was to understand the mechanisms of action of diquafosol,
a stable derivative of uridine 5′-triphosphate, on Cl–transport across the isolated rabbit …

The angiotensin (Ang) type 1 receptor (AT1R) promotes functional and structural integrity of
the arterial wall to contribute to vascular homeostasis, but this receptor also promotes …

The mechanisms by which uridine triphosphate (UTP) stimulates ATP release from Schwann
cells cultured from the sciatic nerve were investigated using online bioluminescence …

Aging has a remarkable effect on cardiovascular homeostasis and it is known as the major
non-modifiable risk factor in the development of hypertension. Medications targeting …

Purpose. The purinergic P2Y 2 receptor agonists stimulate active Cl-transport across the
excised rabbit conjunctival tissue in vitro. We determined whether UTP or ATP could …

The endogenous mechanisms modulating ATP‐induced dopamine release in the nucleus
accumbens (NAc) were studied by microdialysis in freely moving rats. The ATP analog 2 …

Background and purpose: P2Y receptors evoke Ca2+ signals in vascular smooth muscle
cells and regulate contraction and proliferation, but the roles of the different P2Y receptor …