The concentration of sodium ions (Na+) is raised in solid tumours and can be measured at
the cellular, tissue and patient levels. At the cellular level, the Na+ gradient across the …

Since the formation of new blood vessels is essential for tumour growth and metastatic
spread, inhibition of angiogenesis by targeting the vascular endothelial growth factor (VEGF) …

Although ribosome assembly is quality controlled to maintain protein homeostasis, different
ribosome populations have been described. How these form, especially under stress …

The scientific knowledge about tumor metabolism has grown at a fascinating rate in recent
decades. We now know that tumors are highly active both in their metabolism of available …

Significant progress in the characterization of protein corona has been made. However,
insights on how the corona affects the aggregation of nanoparticles (NPs) and consequent …

UVB radiation mediates inflammatory responses causing skin damage and defects in
epidermal differentiation. 1α, 25-Dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3) interacts with the …

Macrophages (MΦ) and dendritic cells (DC), major players of the mononuclear phagocyte
system (MoPh), are potent antigen presenting cells that steadily sense and respond to …

The influx of sodium (Na+) ions into a resting cell is regulated by Na+ channels and by
Na+/H+ and Na+/Ca2+ exchangers, whereas Na+ ion efflux is mediated by the activity of …

Sodium MR imaging has the potential to complement routine proton MR imaging
examinations with the goal of improving diagnosis, disease characterization, and clinical …

Nuclear factor of activated T cells 5 (NFAT5) has recently been classified as a new member
of the Rel family. In addition, there are 5 more well-defined members (NF-κB and NFAT1–4) …