Background & Aims: Liver transplant recipients infected with hepatitis C virus (HCV) develop
recurrent hepatitis soon after transplantation and, in some cases, progress to fibrosis within …

CC motif ligand 5 (CCL5) facilitates induction of chemotaxis in immune cells and activation
of hepatic stellate cells (HSC) at sites of liver inflammation during chronic hepatitis C virus …

The mechanisms of induction of liver injury during chronic infection with hepatitis C virus
(HCV) are not well understood. Gamma interferon (IFN-γ)-inducible protein 10 (IP-10), a …

Hepatitis B virus (HBV) and hepatitis C virus (HCV) are among the most endemic pathogens
worldwide, with more than 500 million people globally currently infected with these viruses …

BACKGROUND: The mechanisms leading to hepatic injury in chronic hepatitis C virus
(HCV) infection are only incompletely understood. Recent data propose a correlation of the …

CD8 T cells play a critical role in several pathological conditions affecting the liver, most
notably viral hepatitis. Accordingly, understanding the mechanisms that modulate the …

Purpose Concurrent infection with HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV)
often occurs due to the commonality in risk factors for acquisition. Few studies have …

The liver is a unique lymphoid organ whose microenvironment is biased towards tolerance
induction. We previously found that a proportion of CD4+ autoreactive recent thymic …

T cells are involved in the pathogenesis of important liver diseases including both
autoimmune liver diseases and viral hepatitis. In addition to playing a crucial role in the …

BACKGROUND & AIMS: Recently, variation of gene copy numbers was recognized as a
novel type of common genetic diversity, but its impact on viral hepatitis is unknown. Here, we …