Overall survival associated with CDK4/6 inhibitors in patients with HR+/HER2–metastatic breast cancer in the United States: A SEER‐Medicare population‐based …

RK Goyal, H Chen, SM Abughosh, HM Holmes… - Cancer, 2023 - Wiley Online Library
Background Evidence on overall survival (OS) with cyclin‐dependent kinase 4 and 6
(CDK4/6) inhibitors is generally limited to data from clinical trials or a few observational …

[HTML][HTML] HR+/HER2− de novo metastatic breast cancer: a true peculiar entity?

R Torrisi, F Jacobs, C Miggiano, R De Sanctis… - Drugs in …, 2023 - ncbi.nlm.nih.gov
De novo metastatic breast cancer (dnMBC) accounts for~ 6–10% of all breast cancers and
for~ 30% of MBC with increasing incidence over time. Hormone receptor-positive/human …

A new paradigm for classifying and treating HER2‐positive breast cancer

X He, SCJ Yeung, FJ Esteva - Cancer Reports, 2023 - Wiley Online Library
Background Because of the phenomenal success of treatment with monoclonal antibodies
and antibody‐drug conjugates targeting human epidermal growth factor receptor 2 (HER2) …

Novel prognostic staging system for patients with de novo metastatic breast cancer

JK Plichta, SM Thomas, DF Hayes… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Given the heterogeneity and improvement in outcomes for metastatic breast
cancer (MBC), we developed a staging system that refines prognostic estimates for patients …

Survival among patients with untreated metastatic breast cancer: “What if I do nothing?

JK Plichta, SM Thomas, X Wang, SGR McDuff… - Breast Cancer Research …, 2024 - Springer
Purpose We sought to assess survival outcomes of patients with de novo metastatic breast
cancer (dnMBC) who did not receive treatment irrespective of the reason. Methods Adults …

Approach to Bone Health in the Patient with Breast Cancer

Y Motlaghzadeh, JY Wu - The Journal of Clinical Endocrinology …, 2024 - academic.oup.com
Abstract Treatment for breast cancer, including endocrine therapies, can contribute to bone
loss and increase the risk of osteoporosis and fractures. Management of bone health in …

Advancing the Role of Proton Therapy for Spine Metastases Through Diagnostic Scan–Based Planning

CW Swanick, MH Shang, K Erhart… - … Journal of Particle …, 2023 - meridian.allenpress.com
Purpose Many patients with metastatic cancer live years beyond diagnosis, and there
remains a need to improve the therapeutic ratio of metastasis-directed radiation for these …

Clinical genetics in breast cancer

KW Ntowe, MS Lee, JK Plichta - Journal of Surgical Oncology, 2024 - Wiley Online Library
As genetic testing becomes increasingly more accessible and more applicable with a
broader range of clinical implications, it may also become more challenging for breast …

Expression of nuclear receptor co‑activator 7 protein is associated with poor prognosis of breast cancer

Z Peng, Y Li, S Xia, Q Dai, L Yin… - Oncology …, 2024 - spandidos-publications.com
Abstract Nuclear receptor coactivator 7 (NCOA7) is an estrogen receptor binding protein. Its
role in breast cancer progression has so far remained elusive. The present study aimed to …

Molecularly imprinted polymers based on attapulgite and sustained-release properties for 5-FU

X Ji, Z Yang, J Fang, S Hu - Colloid and Polymer Science, 2024 - Springer
In this study, a novel molecularly imprinted polymer (MIP) was synthesized with attapulgite
(ATP) and acrylamide (AM) and ethyl methacrylate (MMA) for controlled release carrier of 5 …