Prediction of Anti‐Alzheimer's Activity of Flavonoids Targeting Acetylcholinesterase in silico
Introduction Prenylated and pyrano‐flavonoids of the genus Artocarpus JR Forster & G.
Forster are well known for their acetylcholinesterase (AChE) inhibitory, anti‐cholinergic, anti …
Forster are well known for their acetylcholinesterase (AChE) inhibitory, anti‐cholinergic, anti …
[图书][B] Dementia in clinical practice: a neurological perspective: pragmatic studies in the cognitive function clinic
AJ Larner - 2014 - Springer
What contribution (s) to the diagnosis and care of people with cognitive disorders can a
neurology-led dementia clinic make? Naïve readers of recent United Kingdom policy …
neurology-led dementia clinic make? Naïve readers of recent United Kingdom policy …
Poor safety and tolerability hamper reaching a potentially therapeutic dose in the use of thalidomide for Alzheimer's disease: results from a double-blind, placebo …
B Decourt, D Drumm-Gurnee, J Wilson… - Current Alzheimer …, 2017 - ingentaconnect.com
Introduction: To date there is no cure for Alzheimer's disease (AD). After amyloid beta
immunotherapies have failed to meet primary endpoints of slowing cognitive decline in AD …
immunotherapies have failed to meet primary endpoints of slowing cognitive decline in AD …
[HTML][HTML] In vitro evaluation of the neuroprotective potential of Olea dioica against Aβ peptide-induced toxicity in human neuroblastoma SH-SY5Y cells
PG Kenchappa, Y Karthik, PD Vijendra… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a type of neurodegenerative disease, associated with the
hastening of ROS, acetylcholinesterase (AChE) activity, and amyloid β peptides plaques in …
hastening of ROS, acetylcholinesterase (AChE) activity, and amyloid β peptides plaques in …
Cholinesterase as a target for drug development in Alzheimer's disease
Alzheimer's disease (AD) is an enormous healthcare challenge, and 50 million people are
currently suffering from it. There are several pathophysiological mechanisms involved, but …
currently suffering from it. There are several pathophysiological mechanisms involved, but …
[HTML][HTML] In Vitro Antioxidant, Anti-Diabetes, Anti-Dementia, and Inflammation Inhibitory Effect of Trametes pubescens Fruiting Body Extracts
Trametes pubescens, white rot fungus, has been used for folk medicine in Asian countries to
treat ailments such as cancer and gastrointestinal diseases. This study was initiated to …
treat ailments such as cancer and gastrointestinal diseases. This study was initiated to …
[HTML][HTML] Advances in designs for Alzheimer's disease clinical trials
J Cummings, H Gould, K Zhong - American journal of …, 2012 - ncbi.nlm.nih.gov
There is an urgent need to identify new treatments for the rapidly growing population of
people with Alzheimer's disease (AD). Innovations in clinical trial designs many help to …
people with Alzheimer's disease (AD). Innovations in clinical trial designs many help to …
Computer aided drug design studies in the discovery of secondary metabolites targeted against age-related neurodegenerative diseases
L Scotti, M Tullius Scotti - Current topics in medicinal chemistry, 2015 - ingentaconnect.com
Secondary metabolites are plant products that occur usually in differentiated cells, generally
not being necessary for the cells themselves, but likely useful for the plant as a whole …
not being necessary for the cells themselves, but likely useful for the plant as a whole …
HPLC–DAD characterization of phenolic profile and in vitro antioxidant, anticholinesterase, and antidiabetic activities of five mushroom species from Turkey
In this study, Daedalea quercina (L.) Pers., Hydnum repandum L., Inonotus radiatus
(Sowerby) P. Karst., Omphalotus olearius (DC.) Singer, and Schizophyllum commune Fr …
(Sowerby) P. Karst., Omphalotus olearius (DC.) Singer, and Schizophyllum commune Fr …
Derivatization, molecular docking and in vitro acetylcholinesterase inhibitory activity of glycyrrhizin as a selective anti-Alzheimer agent
Abstract Acetylcholinesterase inhibitors (AChE-Is) increase both level and duration of action
of acetylcholine (ACh); thus, alleviate symptoms of Alzheimer's disease (AD). Glycyrrhizin, is …
of acetylcholine (ACh); thus, alleviate symptoms of Alzheimer's disease (AD). Glycyrrhizin, is …