In this study, the retention behavior of benzimidazole anthelmintic drug mebendazole (MBZ)
was investigated with a liquid chromatographic method. Influence of acetonitrile (ACN) …

Background: Alzheimer's disease is caused by the destruction or loss of cholinergic cells
that produce or use ACh in the brain, thereby reducing the availability of enzyme to other …

A rapid and efficient methodology was performed for the synthesis of α, β-unsaturated
ketones 2a–k containing benzoazonine core through Claisen-Schmidt reaction of the …

Background There is an aging demographic in many countries resulting in an increased
prevalence of age-associated chronic disease, particularly Alzheimer's dementia [AD] and …

Parkinson's Disease (PD) is a neurological disorder characterized by the loss of
dopaminergic neurons of the substantia nigra pars compacta (SNc). Several predisposing …

Welcome to the world of Advanced Medicinal Chemistry, a field that sits at the intersection of
science, innovation, and the relentless pursuit of improving human health. In this book, we …

Tématem diplomové práce je syntéza a následná charakterizace nepopsaných
anticholinergních karbamátů obsahujících benzthiazolový blok. V teoretické části byla …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with an unknown
etiology that accounts for 60-70% of all dementia cases (Burns and Iliffe, 2009; World Health …