Modulation of the carotid baroreceptor reflex by substance P in the nucleus tractus solitarius

JL Seagard, C Dean, FA Hopp - Journal of the autonomic nervous system, 2000 - Elsevier
Previous studies have shown that administration of substance P (SP) into the nucleus tractus
solitarius (NTS) can evoke a depressor response similar to that produced by activation of the …

Anti-emetic effects of a novel NK-1 receptor antagonist HSP-117 in ferrets

R Saito, Y Suehiro, H Ariumi, K Migita, N Hori… - Neuroscience …, 1998 - Elsevier
We have developed a non-peptide compound, HSP-117, antagonist of the tachykinin NK-1
receptor. Binding of 3H-substance P (SP) to the membranes of IM-9 cells was inhibited by …

Bimodal effects of chronically administered neurokinin B (NKB) on in vivo and in vitro cardiovascular responses in female rats

J Yang, V Dhawan, DW Morrish, S Kaufman - Regulatory peptides, 2007 - Elsevier
The in vivo cardiovascular effects of acutely administered neurokinin B (NKB) have been
attributed both to direct effects on vascular tone and to indirect effects on central …

痛みをやわらげる: 神経障害性疼痛の新規治療薬への挑戦

高野行夫 - YAKUGAKU ZASSHI, 2014 - jstage.jst.go.jp
抄録 Pain control is very important since, even today, 20 million people suffer from
neuropathic pain. Although many basic science and clinical researchers have made efforts …