New targeted therapies in pituitary carcinoma resistant to temozolomide

E Jouanneau, A Wierinckx, F Ducray, V Favrel… - Pituitary, 2012 - Springer
To evaluate the antitumoral efficacy of everolimus in pituitary carcinoma resistant to
temozolomide, the correlation with mammalian target of rapamycin (mTOR) signaling in the …

Management of aggressive pituitary adenomas and pituitary carcinomas

A Heaney - Journal of neuro-oncology, 2014 - Springer
Pituitary tumors are benign but not uncommonly invade locally into adjacent tissues such as
the cavernous sinus and dura. Some of these invasive tumors exhibit varying degrees of …

The risks of overlooking the diagnosis of secreting pituitary adenomas

T Brue, F Castinetti - Orphanet journal of rare diseases, 2016 - Springer
Secreting pituitary adenomas that cause acromegaly and Cushing's disease, as well as
prolactinomas and thyrotroph adenomas, are uncommon, usually benign, slow-growing …

Magnetic resonance imaging of pituitary tumors

JF Bonneville - Imaging in endocrine disorders, 2016 - karger.com
Magnetic Resonance Imaging (MRI) is currently considered a major keystone of the
diagnosis of diseases of the hypothalamic-hypophyseal region. However, the relatively …

Immune landscape of pituitary tumors reveals association between macrophages and gonadotroph tumor invasion

M Principe, M Chanal, MD Ilie, A Ziverec… - The Journal of …, 2020 - academic.oup.com
Abstract Purpose Pituitary neuroendocrine tumors (PitNETs) are frequent intracranial
neoplasms that present heterogenic characteristics. Little is known about the immune cell …

Prolactinoma ErbB receptor expression and targeted therapy for aggressive tumors

O Cooper, A Mamelak, S Bannykh, J Carmichael… - Endocrine, 2014 - Springer
As ErbB signaling is a determinant of prolactin synthesis, role of ErbB receptors was tested
for prolactinoma outcomes and therapy. The objective of this study was to characterize ErbB …

[HTML][HTML] The chance of permanent cure for micro-and macroprolactinomas, medication or surgery? A systematic review and meta-analysis

Q Ma, J Su, Y Li, J Wang, W Long, M Luo… - Frontiers in …, 2018 - frontiersin.org
Background: This meta-analysis aims to evaluate the long-term efficacy of medication
treatment vs. surgery treatment in patients with prolactinomas. Methods: An electronic …

Endothelial expression of endocan is strongly associated with tumor progression in pituitary adenoma

A Cornelius, C CortetRudelli, R Assaker… - Brain …, 2012 - Wiley Online Library
Although benign, pituitary adenomas frequently invade adjacent sinuses or recur after first
surgery. To date, there is no histological marker predictive of recurrence. Angiogenic factors …

Giant prolactinoma in children and adolescents: a single-center experience and systematic review

S Kumar, V Sarathi, AR Lila, M Sehemby, SS Memon… - Pituitary, 2022 - Springer
Purpose Giant prolactinoma (GP) in childhood and adolescence is a rare entity with scarce
literature. We aimed to describe clinical features, biochemistry, radiology, genetics …

Reasons and results of endoscopic surgery for prolactinomas: 142 surgical cases

S Akin, I Isikay, F Soylemezoglu, T Yucel, A Gurlek… - Acta …, 2016 - Springer
Background We report herein a retrospective analysis of the results of 142 consecutive
prolactinoma cases operated upon using an endoscopic endonasal trans-sphenoidal …