Roles of transposable elements in the regulation of mammalian transcription

R Fueyo, J Judd, C Feschotte, J Wysocka - Nature reviews Molecular …, 2022 - nature.com
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …

[HTML][HTML] Taming transposable elements in vertebrates: from epigenetic silencing to domestication

MV Almeida, G Vernaz, ALK Putman, EA Miska - Trends in Genetics, 2022 - cell.com
Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …

From telomere to telomere: The transcriptional and epigenetic state of human repeat elements

SJ Hoyt, JM Storer, GA Hartley, PGS Grady… - Science, 2022 - science.org
Mobile elements and repetitive genomic regions are sources of lineage-specific genomic
innovation and uniquely fingerprint individual genomes. Comprehensive analyses of such …

The rise of regulatory RNA

KV Morris, JS Mattick - Nature Reviews Genetics, 2014 - nature.com
Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

Bacterial insertion sequences: their genomic impact and diversity

P Siguier, E Gourbeyre… - FEMS microbiology …, 2014 - academic.oup.com
Insertion sequences (ISs), arguably the smallest and most numerous autonomous
transposable elements (TEs), are important players in shaping their host genomes. This …

[HTML][HTML] Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs

A Kapusta, Z Kronenberg, VJ Lynch, X Zhuo… - PLoS …, 2013 - journals.plos.org
Advances in vertebrate genomics have uncovered thousands of loci encoding long
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …

The impact of retrotransposons on human genome evolution

R Cordaux, MA Batzer - Nature reviews genetics, 2009 - nature.com
Their ability to move within genomes gives transposable elements an intrinsic propensity to
affect genome evolution. Non-long terminal repeat (LTR) retrotransposons—including LINE …

The epigenetic control of the transposable element life cycle in plant genomes and beyond

P Liu, D Cuerda-Gil, S Shahid… - Annual Review of …, 2022 - annualreviews.org
Within the life cycle of a living organism, another life cycle exists for the selfish genome
inhabitants, which are called transposable elements (TEs). These mobile sequences invade …

Transposable elements and the evolution of regulatory networks

C Feschotte - Nature Reviews Genetics, 2008 - nature.com
The control and coordination of eukaryotic gene expression rely on transcriptional and post-
transcriptional regulatory networks. Although progress has been made in mapping the …

DNA transposons: nature and applications in genomics

M Muñoz-López, JL García-Pérez - Current genomics, 2010 - ingentaconnect.com
Repeated DNA makes up a large fraction of a typical mammalian genome, and some
repetitive elements are able to move within the genome (transposons and retrotransposons) …