Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

J Baj, I Korona-Głowniak, A Forma, A Maani, E Sitarz… - Cells, 2020 - mdpi.com
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

[HTML][HTML] The interaction of Helicobacter pylori with cancer immunomodulatory stromal cells: New insight into gastric cancer pathogenesis

JG Navashenaq, AG Shabgah, M Banach… - Seminars in cancer …, 2022 - Elsevier
Gastric cancer is the fourth most common cause of cancer-linked deaths in the world. Gastric
tumor cells have biological characteristics such as rapid proliferation, high invasiveness …

Cancer-associated fibroblasts-derived VCAM1 induced by H. pylori infection facilitates tumor invasion in gastric cancer

J Shen, J Zhai, Q You, G Zhang, M He, X Yao, L Shen - Oncogene, 2020 - nature.com
Cancer-associated fibroblasts (CAFs) play a major role in the progression of stomach
cancer, but the related mechanisms are not fully understood. H. pylori infection is recognized …

Inflammatory microenvironment in gastric premalignant lesions: implication and application

S Zhang, Y Shen, H Liu, D Zhu, J Fang, H Pan… - Frontiers in …, 2023 - frontiersin.org
Gastric precancerous lesions (GPL) are a major health concern worldwide due to their
potential to progress to gastric cancer (GC). Understanding the mechanism underlying the …

Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature

TMJ Eddin, SMO Nasr, I Gupta, H Zayed… - Heliyon, 2023 - cell.com
Gastric cancer, a multifactorial disease, is considered one of the most common malignancies
worldwide. In addition to genetic and environmental risk factors, infectious agents, such as …

Effects of helicobacter pylori on tumor microenvironment and immunotherapy responses

R Deng, H Zheng, H Cai, M Li, Y Shi… - Frontiers in …, 2022 - frontiersin.org
Helicobacter pylori is closely associated with gastric cancer. During persistent infection,
Helicobacter pylori can form a microenvironment in gastric mucosa which facilitates the …

[PDF][PDF] Involvement of epithelial-mesenchymal transition-inducing transcription factors in the mechanism of Helicobacter pylori-induced fibroblasts activation.

G Krzysiek-Maczka, A Targosz, U Szczyrk… - Journal of Physiology …, 2019 - jpp.krakow.pl
Gastric cancer (GC) originating from the lining of the stomach is one of the most frequent
malignancies in humans. The most efficient method giving hope of full recovery from GC is …

Role of Helicobacter pylori infection in cancer‐associated fibroblast‐induced epithelial‐mesenchymal transition in vitro

G Krzysiek‐Maczka, A Targosz, U Szczyrk… - …, 2018 - Wiley Online Library
Background Major human gastrointestinal pathogen Helicobacter pylori (H. pylori) colonizes
the gastric mucosa causing inflammation and severe complications including cancer, but the …

[HTML][HTML] Impact of Helicobacter pylori on the healing process of the gastric barrier

E Mnich, M Kowalewicz-Kulbat, P Sicińska… - World Journal of …, 2016 - ncbi.nlm.nih.gov
AIM To determine the impact of selected well defined Helicobacter pylori (H. pylori) antigens
on gastric barrier cell turnover. METHODS In this study, using two cellular models of gastric …

[PDF][PDF] Oral Helicobacter pylori, its relationship to successful eradication of gastric H. pylori and saliva culture confirmation

XM Wang, KC Yee, N Hazeki-Taylor, J Li, HY Fu… - J Physiol …, 2014 - jpp.krakow.pl
The present study was designed to explore the existence of oral Helicobacter pylori (H.
pylori), its relationship in the oral cavity to the success rate of eradication of the gastric H …