La introducción de los antibióticos en la práctica clínica supuso una de las intervenciones
más importantes para el control de las enfermedades infecciosas. Los antibióticos han …

Over the past two decades, the diagnosis rate for patients with encephalitis has remained
poor despite advances in pathogen-specific testing such as PCR and antigen assays …

Importance The development of antibiotics is considered among the most important
advances of modern science. Antibiotics have saved millions of lives. However …

Importance Because clinical features do not reliably distinguish bacterial from viral infection,
many children worldwide receive unnecessary antibiotic treatment, while bacterial infection …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus
disease-19 (COVID-19), has emerged as the cause of a global pandemic. We used RNA …

Acute respiratory infections caused by bacterial or viral pathogens are among the most
common reasons for seeking medical care. Despite improvements in pathogen-based …

Improved diagnostics for acute infections could decrease morbidity and mortality by
increasing early antibiotics for patients with bacterial infections and reducing unnecessary …

Importance Young febrile infants are at substantial risk of serious bacterial infections;
however, the current culture-based diagnosis has limitations. Analysis of host expression …

Bacterial and viral infections are often clinically indistinguishable, leading to inappropriate
patient management and antibiotic misuse. Bacterial-induced host proteins such as …

SARS-CoV-2 infection has been shown to trigger a wide spectrum of immune responses
and clinical manifestations in human hosts. Here, we sought to elucidate novel aspects of …