The human microbiome in disease and pathology

J Manos - Apmis, 2022 - Wiley Online Library
This narrative review seeks to examine the relationships between bacterial microbiomes
and infectious disease. This is achieved by detailing how different human host microbiomes …

The contribution of the human oral microbiome to oral disease: a review

AG Morrison, S Sarkar, S Umar, STM Lee, SM Thomas - Microorganisms, 2023 - mdpi.com
The oral microbiome is an emerging field that has been a topic of discussion since the
development of next generation sequencing and the implementation of the human …

Understanding dental caries as a non-communicable disease

NB Pitts, S Twetman, J Fisher, PD Marsh - British dental journal, 2021 - nature.com
The recent developments in the science underpinning our knowledge of both the initiation of
dental caries and the subsequent behaviour of lesions over time gives us a solid base to …

Armed to the teeth—the oral mucosa immunity system and microbiota

M Ptasiewicz, E Grywalska, P Mertowska… - International Journal of …, 2022 - mdpi.com
The oral cavity is inhabited by a wide spectrum of microbial species, and their colonization is
mostly based on commensalism. These microbes are part of the normal oral flora, but there …

Optimizing the quality of clinical studies on oral microbiome: A practical guide for planning, performing, and reporting

E Zaura, VY Pappalardo, MJ Buijs… - Periodontology …, 2021 - Wiley Online Library
With this review, we aim to increase the quality standards for clinical studies with
microbiome as an output parameter. We critically address the existing body of evidence for …

Addition of cariogenic pathogens to complex oral microflora drives significant changes in biofilm compositions and functionalities

Y Liu, SG Daniel, HE Kim, H Koo, J Korostoff, F Teles… - Microbiome, 2023 - Springer
Background Dental caries is a microbe and sugar-mediated biofilm-dependent oral disease.
Of particular significance, a virulent type of dental caries, known as severe early childhood …

Oral microbiome composition, but not diversity, is associated with adolescent anxiety and depression symptoms

CA Simpson, C Adler, MR du Plessis, ER Landau… - Physiology & …, 2020 - Elsevier
Purpose Depression and anxiety are highly prevalent disorders, whose significant burden is
compounded by the presence of oral disease. Mental health disorders and oral health may …

Oral microbiota composition predicts early childhood caries onset

A Grier, JA Myers, TG O'Connor… - Journal of dental …, 2021 - journals.sagepub.com
As the most common chronic disease in preschool children in the United States, early
childhood caries (ECC) has a profound impact on a child's quality of life, represents a …

Impact of breastfeeding and other early-life factors on the development of the oral microbiome

RA Arishi, CT Lai, DT Geddes, LF Stinson - Frontiers in Microbiology, 2023 - frontiersin.org
The oral cavity is home to the second most diverse microbiome in the human body. This
community contributes to both oral and systemic health. Acquisition and development of the …

Development of the oral resistome during the first decade of life

S Sukumar, F Wang, CA Simpson, CE Willet… - Nature …, 2023 - nature.com
Antibiotic overuse has promoted the spread of antimicrobial resistance (AMR) with
significant health and economic consequences. Genome sequencing reveals the …