Investigation of cerebrospinal fluid (CSF) in the diagnostic work-up in suspected multiple
sclerosis (MS) patients has regained attention in the latest version of the diagnostic criteria …

Multiple sclerosis (MS) has traditionally been considered to be a T-cell-mediated disease.
However, there is an increasing body of evidence for the involvement of B cells and …

In patients with multiple sclerosis (MS) intensive efforts are directed at identifying biomarkers
in bodily fluids related to underlying disease mechanisms, disease activity and progression …

The clinical course of multiple sclerosis (MS) is highly variable among patients, thus creating
important challenges for the neurologist to appropriately treat and monitor patient progress …

Introduction Multiple sclerosis (MS) is the most frequent demyelinating disease of the central
nervous system. Although there is currently there is no definite cure for MS, new therapies …

The natural history of relapsing remitting multiple sclerosis (RRMS) is variable and
prediction of individual prognosis challenging. The inability to reliably predict prognosis at …

Multiple sclerosis (MS), a debilitating autoimmune inflammatory disease that affects the
brain and spinal cord, causes demyelination of neurons, axonal damage, and …

We reviewed the records of 391 patients who had presented with a Clinically Isolated
Syndrome and selected 205 who had performed a baseline spinal tap and MRI scan. We …

Objective To determine the best method to measure intrathecal immunoglobulin (Ig) M
synthesis (ITMS), a biomarker of worse prognosis in multiple sclerosis (MS). We compared …

Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system,
usually occurring in young adults and leading to disability. Despite the progress in …